Cytokines are essential modulators of the immune response. In the last decade there has been a number of cytokines considered targets for the development of biological therapies with the goal of blocking their activities and modulate the course of the immune response, primarily in the context of inflammatory diseases. IL-6 was first identified in the mid-1980s [1], but for almost two decades th...

Note: G/C polymorphism at nucleotide -174 (promoter region) Breast cancer prognosis differs between populations. Despite its lower incidence in Blacks when compared to Caucasians, mortality among the former is higher. Genetic factors involved in the molecular pathways regulating tumor development have been adduced to explain these differences, and it has been suggested that the IL-6 gene is a s...

background: interleukin-6 (il-6) is one of the inflammatory mediators characterized by elevated levels in ischemic stroke (is) patients. the present study set out to assess the role of il-6, as a marker for inflammation, in the severity and prognosis of acute is. methods: in a cross-sectional descriptive study, 45 patients with acute is were selected. patients with their first day of stroke wer...