Lung cancer is one of the most common types of cancer and is the leading cause of cancer-related mortality worldwide. Estrogens are known to be involved in the development and progression of non-small-cell lung cancer (NSCLC). These effects are initially mediated through binding of estrogen to estrogen receptors (ERs), in particular ERβ2. Our preliminary studies demonstrated that ERβ2 and inter...

Abstract Introduction Sleep disturbance is a prominent concern in patients with cancer detrimental effect on health outcomes. Although inflammation has been proposed as potential mechanism of sleep disturbance, there dearth longitudinal data supporting the relationship between cancer-related and inflammatory markers. The goal this prospective study was to examine change quality its association ...