Background: The purpose of this study was to identify the effects of eight weeks of conventional and suspension corestability exercises by use of the designed device on characteristic of intervertebral discs in low back pain.Methods: A total of 27 men with chronic low back (CLB) pain due to lumbar disc herniation in L4-L5 and L5-S1 regionswere enrolled in this quasi-experiment...

STUDY DESIGN Coil springs were stretched and attached to produce a compressive force across the lumbar intervertebral discs of dogs for up to 53 weeks. OBJECTIVE To test the hypothesis that compressive forces applied to the intervertebral disc for a long period of time cause disc degeneration in vivo in a dog model. SUMMARY OF BACKGROUND DATA It is a commonly held belief that high forces ap...

BACKGROUND The natural, inflammatory repair processes of an injured intervertebral degenerative disc can propagate further injury and destruction. While there are many different treatment modalities of the pain related to degenerative disc disease, none are actually reparative in nature. Treatment strategies to repair a degenerative disc without inducing a destructive inflammatory milieu have b...

Discitis after discography is due to bacterial penetration into the intervertebral disc by a contaminated needle and has an incidence of 1% to 4%. We have examined the prophylactic role of cephazolin administered at the time of discography. An experimental study in sheep using radiographic contrast containing Staphylococcus epidermidis showed that either adding the antibiotic to the intradiscal...

Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is a complex multifactorial process. Animal models are essential to furthering understanding of the degenerative process and testing potential therapies. The adult human lumbar intervertebral disc is characterized ...

BACKGROUND The effect of the menopause and HRT on the intervertebral discs has not been investigated. METHODS One hundred women were recruited, comprising of 44 post-menopausal women on HRT, 33 untreated post-menopausal women and 23 pre-menopausal women. The height of the intervertebral discs between the 12th thoracic vertebra and the 3rd lumbar vertebra was measured by utilizing the bone den...

Cramps in the affected leg are quite common and persistent although sciatic pain may have disappeared completely. A small proportion of patients develop a true recurrent prolapse (prolapse from the same disc) months to years later. This varies in individual statistics, but is probably in the neighbourhood of 4 per cent. to 5 per cent. These recurrent attacks of sciatica, due to a further protru...

Neurology lays many claims to being one of the more precise and scientific branches of medicine but, nevertheless, there have been several neurological conditions almost mediaeval in their conceptions. One of these is a group included under the general heading of the neuritides-namely, sciatic and brachial neuritis and neuralgia. There is now a large body of evidence to show that the humoral, a...

The annulus fibrosus is the primary load-bearing component of the intervertebral disc responsible for proper transfer of loads in the spine. The aim of this study was to determine selected mechanical parameters of multilayer specimens of the annulus fibrosus of the intervertebral disc during uniaxial tensile loading. The anatomical location (anterior/posterior) of the test specimens of the annu...

Degeneration of the intervertebral disk and its treatments are currently intensely investigated topics. Back pain is a condition whose chronic and debilitating nature combined with its prevalence make it a major health issue of substantial socioeconomic importance. Although researchers, and even sometimes clinicians, focus on the degenerated disk as the problem, to most patients, pain is the fa...