Using control method to explain medical phenomenon is currently a hot subject of research. The traditional Chinese drug fumigation steaming treat protrusion of protrusion of protrusion of lumbar intervertebral disc with steam generated by boiling medicinal herbs, and this process is a typical non-linear, multivariable, and strong coupling. Experienced nurse and doctor cure patient by their expe...

AIM Gene expression profiles for intervertebral disc (IVD) cells treated with different osmolarities were compared to identify key genes associated with intervertebral disc diseases. MATERIALS AND METHODS Microarray data was downloaded from Gene Expression Omnibus (GEO) database and pre-processed using package of R. Gene co-expression was determined with Pearson correlation coefficient. Inter...

BACKGROUND The present study was conducted to address whether the intervertebral disc of rabbit could be considered (i) as a valuable model to provide new insights into the tissue and cellular changes of Nucleus pulposus aging and (ii) as an appropriate tool to investigate the efficacy of Nucleus pulposus cell-based biotherapies. METHODS Lumbar intervertebral disc from rabbits with increasing...

BACKGROUND An association between the occurrence of calcified discs, visible on radiographic examination (CDVR), and disc extrusions has been suggested in published literature over the past 10-20 years, mainly from Nordic countries. It has also been postulated that dogs without CDVR would not develop disc extrusions. Furthermore, inheritance of CDVR has been calculated and it has been postulate...

Intervertebral disc degeneration, a major cause of chronic low back pain, is caused by irreversible changes inthe nucleus pulposus cells that make up part the disc. In recent years, regenerative medicine for intervertebraldisc degeneration through administration mesenchymal stem (MSCs) and cytokines has been performed. Dedifferentiated fat (DFAT) are MSC-like multipotent can be prepared ceiling...

Intradural disc herniation has been reported as a rare type of intervertebral disc herniation, only 32 cases reported. It remains difficult to definitively diagnose the disease before surgery. We reported a 55 year-old female patient complaints of nuchal pain and bilateral arm weakness after a trauma accident. MRI revealed a C3-C4 herniated intervertebral disc (HIVD) with a “hawk-beak sign.” CT...

Intervertebral disc herniation of the lumbar spine is a common disease presenting with low back pain and involving nerve root radiculopathy. Some neurological symptoms in the majority of patients frequently improve after a period of conservative treatment. This has been regarded as the result of a decrease of pressure exerted from the herniated disc on neighboring neurostructures and a gradual ...

Intervertebral disc degeneration remains a pervasive and intractable disease arising from a combination of aging and stress on the back and spine. The growing field of regenerative medicine brings the promise of stem cells in the treatment of disc disease. Scientists and physicians hope to employ stem cells not only to stop, but also reverse degeneration. However, there are many important outst...

Posterior fixation of intervertebral discs is used to treat, and occasionally diagnose, discogenic pain since it is thought that it will reduce the internal loading of the discs in vitro. We measured the internal loading of ten intervertebral discs using stress profilometry under simulated physiological loads and then after posterior fixation. Partial discectomies were performed to simulate adv...

STUDY DESIGN Prospective study of changes in intervertebral disc degeneration after injection of bupivacaine. PURPOSE To examine whether injection of bupivacaine into human intervertebral discs accelerates their degeneration. OVERVIEW OF LITERATURE Bupivacaine is commonly used for therapy and diagnosis of discogenic low back pain. However, several in vitro studies have reported toxic effect...