It is now 10 years since the first case reports of the use of intravenous lipid emulsion (ILE) as treatment for local anaesthetic systemic toxicity (LAST). In spite of very scarce data on efficacy, safety and mechanism of action, this novel therapy was enthusiastically adopted by anaesthesiologists, clinical toxicologists and emergency medicine physicians worldwide. However, recent thoroughly p...

I T seems implausible that an injection of a simple, off-theshelf, intravenous nutritional solution could be acutely life-saving for a patient with severe drug overdose. But dozens of published case reports support this observation, first made more than a decade ago in a rodent model of bupivacaine toxicity. It is even more surprising that such a simple formulation can rapidly reverse severe cl...

abstract         background and objective: methamphetamine has strong stimulating effects on various systems of the human body. the aim of this study was to evaluate the hematological and biochemical parameters in methamphetamine addicts and to compare them with healthyindividuals.      methods: this is a retrospective case-control study that was conducted in 1390-91 in ibn sina hospital in shi...