background: echinococcus multilocularis is a tiny tapeworm, responsible for 0.3~0.5 million alveolar echinococcosis in humans. methods: we searched relevant papers published between 1981 and 2013 based on the database sources such as pubmed and google scholar, and collected and integrated the data for analysis. results: the parasite is able to use host-originated molecules to modulate its devel...

background and objectives: silymarin is a unique flavonoid complex with documented hepatoprotective properties. silybum  marianum hairy root culture as a source for producing silymarin has been an important strategy for study the cell signaling pathway. in the present investigation trichoderma strains- silybum marianum hairy root cultures interactions have been studied. methods: the effects of ...

metabolic syndrome (mets) is characterized by a cluster of cardiovascular risk factors that include: abdominal obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. recent genome wide association studies have identified several susceptibility regions involved in lipid metabolism that are also associated with mets. we have explored the association of 9 genetic ...

infection with human immunodeficiency virus (hiv) is a progressive condition which may cause endothelial dysfunction and liver damage leading to coagulopathy. with adventure of highly active antiretroviral therapy (haart), life expectancy has prolonged in hiv positive patients but several acquired immunodeficiency syndrome (aids)-related conditions such as coagulopathies are responsible for ass...

in plants, γ-aminobutyric acid (gaba) is synthesized by polyamine degradation pathway besides gaba shunt. aminoguanidine (ag) is a specific inhibitor of the key enzyme (diamine oxidase, dao) for gaba formation in polyamine degradation pathway. in this study, ag was applied to study the functions of polyamine degradation pathway on growth and gaba accumulation in germinating fava bean under hypo...

mycobacterium tuberculosis, the main cause of tuberculosis (tb), has still remained a global health crisis especially in developing countries. tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. recently, there has been an alarming rise of drug resistant in tb. in this regard, it is an unmet need...

apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

punica granatum (pg), commonly known as pomegranate (pg), is a member of the monogeneric family, punicaceae, and is mainly found in iran which is considered to be its primary centre of origin. pg and its chemical components possess various pharmacological and toxicological properties including antioxidant, anti-inflammatory (by inhibiting pro-inflammatory cytokines), anti-cancer and anti-angiog...

objectives: auditory brain stem response (abr) is a result of eight nerve and brain stem nuclei stimulation. several factors may affect the latencies, interpeak latencies and amplitudes in abr especially sex and age. in this study, age and sex influence on abr were studied. methods: this study was performed on 120 cases (60 males and 60 females) at akhavan rehabilitation center of university of...

in biotechnology has been concentrated to review alternative routes for the production of natural compounds. plant cell culture systems are viable alternatives for the production of secondary metabolites that are of commercial importance in food and pharmaceutical industries. however, relatively very few cultures synthesize these compounds over extended periods in amounts comparable to those fo...