Medical workers are exposed to chronic low dose ionizing radiation from a variety of sources. Potential cancer risks associated with ionizing radiation exposures have been derived from cohorts experiencing acute high intensity exposure, most notably the Japanese atomic bomb survivors. Since such extrapolations are subject to uncertainty, direct information on the risk associated with chronic lo...

Introduction: Ionizing radiations are the hazardous agents in the workplace and all forms of ionizing radiation produce some type of injuries. Awareness of application of protection guidelines and knowledge of the principles of radiation protection can play an important role in health of employees. Survey of radiation employee’s levels of awareness and practical behavior is essential and ...

The space environment consists mainly of high-energy charged particles, such as protons, electrons and heavy ions. They are originating from several sources including galactic cosmic radiation, solar flares and van Allen belts. High energy electromagnetic radiation and neutrons have also been measured on spacecraft. Although shielding can reduce the effect of space radiation it cannot be elimin...

The mouse Aprt locus on chromosome 8 was used as the selectable target for the study of spontaneous and ionizing radiation-induced mutations in kidney epithelia and ear fibroblasts. Fifty-two Aprt heterozygous mice were exposed to 7.5 Gy of (137)Cs-gamma radiation on their right sides, and Aprt-deficient clones were isolated from enzymatically digested tissues at times ranging from 1 day to 14 ...

During the first hour after a sublethal dose of ionizing radiation, 72 genes were upregulated threefold or higher in D. radiodurans R1. Thirty-three of these loci were also among a set of 73 genes expressed in R1 cultures recovering from desiccation. The five transcripts most highly induced in response to each stress are the same and encode proteins of unknown function. The genes (ddrA, ddrB, d...

OBJECTIVES Although veterinary workers may encounter various occupational health hazards, a national characterization of exposures is lacking in Canada. This study used secondary data sources to identify veterinary exposure prevalence for ionizing radiation and antineoplastic agents, as part of a national surveillance project. METHODS For ionizing radiation, data from the Radiation Protection...

Ionizing radiation produces a variety of damaging insults to nucleic acids, including the promutagenic lesion 8-hydroxydeoxyguanosine. In the present study, the 8-hydroxydeoxyguanosine content of peripheral blood leukocyte DNA isolated from individuals exposed to therapeutic doses of ionizing radiation was determined by a HPLC-coupled 32P-postlabeling assay. Peripheral blood leukocyte DNA from ...