The carbon aerogels prepared by a new method through gelation and supercritical drying in isopropanol were characterized by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy, and a surface area analyzer. Their chemical structure, morphology, and pore structure are discussed. We found that all of these carbon aerogel (CA-IPA) samples have almost the same carbon and oxygen elem...

Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of immunocompromised humans caused by the ubiquitous environmental mold Aspergillus. Biomarker tests for the disease lack sensitivity and specificity, and culture of the fungus from invasive lung biopsy is slow, insensitive, and undesirable in critically ill patients. A computed tomogram (CT) of the chest offers a simple ...

we report an unusual case of co?infection of invasive pulmonary aspergillosis (ipa) and fusarial skin infection in a patient with classic pyoderma gangrenosum with unknown causes, which were previously controlled with oral prednisolone, cyclosporine. the diagnosis was made on direct microscopy and culture of endobronchial washing, bronchoalveolar lavage and skin lesion biopsy. the treatment fai...

19 Invasive pulmonary aspergillosis (IPA) is a life threatening disease of 20 immunocompromised patients that requires aggressive therapy. Detection and monitoring 21 therapeutic response during IPA is complex and current molecular diagnostics are not 22 suitably robust. Here, we explored proteomic profiles of bronchoalveolar lavage fluid 23 (BALF) specimens from a persistently neutropenic rabb...

BACKGROUND Invasive pulmonary aspergillosis (IPA) is a significant problem in patients with chemotherapy-induced prolonged neutropenia. Because pulmonary deposition of conidia is the first step in developing IPA, we hypothesized that inhalation of liposomal amphotericin B would prevent IPA. METHODS We performed a randomized, placebo-controlled trial of patients with hematologic disease with e...

BACKGROUND Early diagnosis and treatment of invasive pulmonary aspergillosis (IPA) improves outcome. METHODS We compared the performance of publicly available pan-Aspergillus, Aspergillus fumigatus-, and Aspergillus terreus-specific real-time polymerase chain reaction (PCR) assays with the Platelia galactomannan (GM) assay in 150 bronchoalveolar lavage (BAL) samples from lung transplant recip...

BACKGROUND Invasive pulmonary aspergillosis (IPA) is a major cause of morbidity and mortality in patients with hematological malignancies in the setting of profound neutropenia and/or hematopoietic stem cell transplantation. Early diagnosis and therapy has been shown to improve outcomes, but reaching a definitive diagnosis quickly can be problematic. Recently, galactomannan testing of bronchoal...

INTRODUCTION Critically ill immunocompromised (CIIC) patients with pulmonary infection are a population at high risk for invasive pulmonary aspergillosis (IPA). The host defenses are important factors to consider in determining the risk and outcome of infection. Quantification of changes in the status of host immunity could be valuable for clinical diagnosis and outcome prediction. METHODS We...

Regression testing is a time consuming, costly process of re-running existing test cases. As software evolves, the regression test suite grows in size. Test case prioritization techniques help by ordering test cases such that at least the test cases which cover the changes made in the software are executed amidst resource and time constraints. Genetic Algorithm (GA) has been widely used for tes...

Two novel Zn(II) metal-organic frameworks (MOFs) constructed by trinuclear-triangular and paddle-wheel units, namely {[Zn(5)(dmtrz)(3)(IPA)(3)(OH)]·DMF·H(2)O}(n) (MAC-4, Hdmtrz = 3,5-dimethyl-1H-1,2,4-triazole, H(2)IPA = isophthalic acid, DMF = dimethyl formamide) and {[Zn(5)(dmtrz)(3)(OH-IPA)(3)(OH)]·DMF·5H(2)O}(n) (MAC-4-OH, OH-H(2)IPA = 5-hydroxyisophthalic acid), were solvothermally synthes...