We address conditional de-Gaussification of continuous variable states by inconclusive photon subtraction (IPS) and review in details its application to bipartite twin-beam state of radiation. The IPS map in the Fock basis has been derived, as well as its counterpart in the phase-space. Teleportation assisted by IPS states is analyzed and the corresponding fidelity evaluated as a function of th...

Employment is a key to community reintegration for both people with mental illness and those with justice involvement. At present, the empirical literature on employment services for justice-involved people with or without mental illness is meager. By contrast, an extensive evidence base documents the effectiveness of a specific employment model for people with severe mental illness: the Indivi...

Ataxia telangiectasia is a neurodegenerative inherited disease with chromosomal instability and hypersensitivity to ionizing radiation. iPS cells lacking ATM (AT-iPS cells) exhibited hypersensitivity to X-ray irradiation, one of the characteristics of the disease. While parental ataxia telangiectasia cells exhibited significant chromosomal abnormalities, AT-iPS cells did not show any chromosoma...

This chapter describes the methods we use to derive and characterize human induced pluripotent stem (iPS) cells. We describe in order, first our culture techniques for the starting fibroblast populations and methods for retrovirus preparation and concentration. Subsequently, a detailed iPS derivation protocol suitable for human fibroblast populations is discussed using standard retroviral vecto...

Reprogramming somatic cells into an ESC-like state, or induced pluripotent stem (iPS) cells, has emerged as a promising new venue for customized cell therapies. In this study, we performed directed differentiation to assess the ability of murine iPS cells to differentiate into bone, cartilage, and fat in vitro and to maintain an osteoblast phenotype on a scaffold in vitro and in vivo. Embryoid ...

When reading a narrative text, both the dorsal and ventral visual systems are activated. To illustrate the patterns of interactions between the dorsal and ventral visual systems in text reading, we conducted analyses of functional connectivity (FC) and effective connectivity (EC) in a left-hemispheric network for reading-driven functional magnetic resonance imaging (fMRI) and resting-state fMRI...

Previous work suggests that when the eye starts at different orbital initial positions (IPs), the saccade control system is faced with significant nonlinearities. Here we studied the effects of IP on saccade-related firing of monkey abducens neurons by either isolating saccade variables behaviorally or applying a multiple linear regression analysis. Over a 50 degrees range of IPs, we could sele...

BACKGROUND An international six-centre randomised controlled trial comparing individual placement and support (IPS) with usual vocational rehabilitation for people with serious mental illness found IPS to be more effective for all vocational outcomes. AIMS To determine which patients with severe mental illness do well in vocational services and which process and service factors are associated...

This study compared elderly hearing aid (EHA) users and elderly normal-hearing (ENH) individuals on identification of auditory speech stimuli (consonants, words, and final word in sentences) that were different when considering their linguistic properties. We measured the accuracy with which the target speech stimuli were identified, as well as the isolation points (IPs: the shortest duration, ...

Induced pluripotent stem (iPS) cell reprogramming is a gradual epigenetic process that reactivates the pluripotent transcriptional network by erasing and establishing repressive epigenetic marks. In contrast to loci-specific epigenetic changes, heterochromatin domains undergo epigenetic resetting during the reprogramming process, but the effect on the heterochromatin ultrastructure is not known...