Vibrational spectroscopy has produced valuable information for biomedical research owing to its label-free and high-throughput capabilities. However, the complexity of large number variables spectral datasets seen increasing application multivariate analysis (MVA) machine learning algorithms in recent years. In particular, use these techniques applied IR spectra biological samples been demonstr...

A novel oxide-supported Ir dimer, which was found to be active for transfer hydrogenation of aromatic ketones, was prepared on a γ-Al(2)O(3) surface from an Ir dimer complex [Ir(2){η(5)-C(5)(CH(3))(5)}(2)(μ-CH(2))(2)] (Ir(2)) with an Ir=Ir bond. Detailed characterization of the γ-Al(2)O(3)-supported Ir dimer (Ir(2)/γ-Al(2)O(3)) revealed that the structure of Ir(2) consisted of an Ir dimer with ...

The aim of this study was to gain insight into the mechanism by which members of the K(ir)2 subfamily are differentially sensitive to agents that inhibit mitochondrial function by identifying responsible site(s) in K(ir)2 proteins. K(ir)2 channels were expressed in Xenopus laevis oocytes and assayed by two-electrode voltage clamp and patch clamp. Incubation of oocytes in carbonyl cyanide p-trif...