BACKGROUND/AIM Reactive oxygen species (ROS) are involved in the development of certain neuropsychiatric disorders. Paraoxonase 1 (PON1) activity has been suggested to be adversely related to oxidative stress in plasma. The purpose of the present study was to demonstrate the relationship between serum PON1 activity and PON1 192 polymorphism in panic disorder (PD). MATERIALS AND METHODS Fourty...

Abstract Introduction CRANIAL (CSF Rhinorrhoea After Endonasal Intervention to the Skull Base) is a prospective, multicentre observational study seeking determine: scope of skull base repair methods used, and corresponding rates postoperative CSF rhinorrhoea in endonasal transsphenoidal (TSA) expanded approaches (EEA) for tumours. Method A cohort pilot was carried out at eleven neurosurgical un...

Radiographic images can provide quantitative as well as quantitative information if they are subjected to densitometric analysis. Digital radiography consists of four major steps which include X-ray detection, digitization, image processing and display. The digitization process varies from device to device and may suffer variations even when the same digital equipment is used throughout time. A...

High dose rate brachytherapy has attained the good local control for cervix cancer because radioactive source can be put close to tumors, resulting in increasing the dose delivery per one fraction. However, quality assurance must be accompanied to reduce severe complication. We verified the dose distribution around the source by comparing measured dose with calculated dose by Radiation Therapy ...

The scintillator with optical fiber (SOF) dosimeter consists of a miniature scintillator mounted on the tip of an optical fiber. The scintillator of the current SOF dosimeter is a 1-mm diameter hemisphere. For a scintillation dosimeter coupled with an optical fiber, measurement accuracy is influenced by signals due to Cerenkov radiation in the optical fiber. We have implemented a spectral filte...

TGF-β1 upregulates microRNA-192 (miR-192) in cultured glomerular mesangial cells and in glomeruli from diabetic mice. miR-192 not only increases collagen expression by targeting the E-box repressors Zeb1/2 but also modulates other renal miRNAs, suggesting that it may be a therapeutic target for diabetic nephropathy. We evaluated the efficacy of a locked nucleic acid (LNA)-modified inhibitor of ...

This report describes a rare case of metastatic hepatocellular carcinoma (HCC) presenting a huge mass in the left external auditory canal (EAC). The patient was a 55-year-old man with hepatitis B virus-related HCC. He presented to our department with a three-month history of increasing left otalgia, and hearing loss with recent fresh aural bleeding. Histopathologic examination indicated that th...