introduction: scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (amps) have been found in the venom gland of scorpions. therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. here, we describe three new cationic amps, including meuvap-6, meuap-18-1, and meupep34 from the ve...

The most important health-threatening scorpions found in Turkey are; Androctonus crassicauda, Leiurus quinquestriatus, Mesobuthus gibbosus and M. eupeus species, all of which belong to the Buthidae family. The epidemiological and clinical findings of scorpion stings in Turkey were evaluated between the years 1995 and 2004 based on data recorded in the National Poison Information Center (NPIC). ...

BACKGROUND Scorpion venom is important and rich source of peptides, most of which have been widely used as pharmacological tools for unraveling structure-function relationship of various ion channels. Naturally occurring toxins can be also considered as lead compounds in the development of novel drugs. OBJECTIVES In this context, the scorpion-derived peptide neurotoxins specific to sodium cha...

The venoms of Buthidae scorpions are known to contain basic, single-chain protein -toxins consisting of 60-70 amino acid residues that are tightly cross-linked by four disulfide bridges. Total RNA was extracted from the venom glands of scorpion Mesobuthus eupeus collected from the Khuzestan province of Iran and then cDNA was synthesized with the modified oligo (dT) primer and extracted total R...

  Introduction: Iranian scorpion species are classified in Buthidae and Scorpionidae with 16 genera and 25 species. In Iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming. Mesobuthus eupeus is the most common species in Iran. Its venom contains several toxin fractions which can affect the ion...

The biotopical distribution, size and age structure of the population, nocturnal activity rhythm feeding mottled scorpion (Mesobuthus eupeus) were studied. research was conducted on left bank Pirsagat river (Shirvan plain, Istern Azerbaijan). All discovered individuals scorpions divided into 5 groups by length metasome. distribution had a pronounced aggregated character with formation local clu...

rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints as well as other organs in the body. adjuvant-induced arthritis models in inbred rats serve as relevant models for ra, having many clinical similarities to this disease. using honey bee venom as a treatment for rheumatoid arthritis is an ancient therapy in various parts of the world. however scorpion ve...