Accepted on 25 th August 2014 _____________________________________________________________________________ ABSTRACT Synthesis of symmetrical Schiff bases (1-4) employed by using condensation methods. Purity was monitored by TLC and column chromatographic techniques. In this present study cyclic voltammetric behavior of symmetrical Schiff bases (1-4) were studied. The cyclic voltammetric studie...

Tuberculosis (TB) remains among the world's great public health challenges. Worldwide resurgence of TB is due to two major problems: the AIDS epidemic, which started in the mid-1980s, and the outbreak of multidrug resistant (MDR) TB. Thus, there is an urgent need for anti-TB drugs with enhanced activity against MDR strains. In recent years, Schiff bases of 1H-indole-2,3-diones are reported to e...

Two biologically active Schiff bases, C13H10BrON (4), C13H9Br2O2N (5), were synthesized by the reaction of 2-aminophenol (1) with 3-bromobenzaldehyde (2) or 3,5-dibromo-4hydroxybenzaldehyde (3) in the presence of conc. H2SO4. The characterization of Schiff bases were carried out by using spectroscopic techniques including IR, H-NMR, FAB-MS along with elemental analyses. The Schiff bases were ch...

Three new Schiff bases of N-substituted isatin L(I), L(II,) and L(III) = Schiff base of N-acetylisatin, N-benzylisatin, and N-benzoylisatin, respectively, and their metal complexes C(1a,b) = [Co(2)(L(I))(2)Cl(3)]Cl, C(2) = [Ni(L(I))(2)Cl(2)]0.4BuOH, C(3) = [CuL(I)Cl(H(2)O)]Cl 0.5BuOH, C(4) = [Pd(L(I))(2)Cl]Cl, C(5) = [Pt(L(1))(2)Cl(2)]Cl(2) 1.8EtOH.H(2)O, C(6a) = [CoL(II)Cl]Cl 0.4H(2)O 0.3DMSO,...

Different Schemes for the synthesis of Schiff bases have been discussed. Solvent free synthesis by microwave irradiation technique is observed to be rapid, more efficient and more economical and at the same time may play a pivotal role in the progress of Schiff base synthesis. Mechanism for the synthesis of Schiff bases at controlled pH range has been studied. Biological functions of metal comp...

Schiff bases, having azomethine (RHC=N-R’) group and their metal complexes are widely used for industrial purposes and also reveal a wide range of biological applications. This review describes the most promising biological activities of Schiff bases and their metal complexes of cerium. A general idea for synthetic methodologies used for the synthesis of Schiff bases and their metal complexes i...

Two new symmetrical Schiff bases have been prepared by the condensation of ethylenediamine and two benzaldehyde derivatives, 2-hydroxybenzaldehyde and 2,4-dimethoxybenzaldehyde. The electronic transitions within these Schiff bases molecules in chloroform solvent have been investigated by UV-Vis spectroscopy. The 1H NMR and IR spectra were studied and assigned to related groups. Furthermore,...

In order to evaluate the influence of substitution on biological properties of Schiff bases and their metal complexes, a series of differently substituted fluorine-containing Schiff bases starting from the drug isoniazid (isonicotinylhydrazide) were prepared and their structures were established by single-crystal X-ray diffraction. Also, four copper(II) complexes of these Schiff bases were synt...