background:  intravenous  recombinant  tissue plasminogen  activator  (rt-pa) is an approved  treatment for acute ischemic stroke within 4.5 h of symptoms onset. decompressive craniectomy (dc) has been  shown  as an effective  therapeutic  modality in malignant  middle cerebral  artery (mca) infarction. as rt-pa could result in hemorrhagic  complication during or after any surgery dc may be ass...

background: although the risk factors of ischemic strokes are well defined, there is slight information about their relations with the etiologies of ischemic strokes. this study investigated the distribution of ischemic stroke risk factors and their connections to diverse etiologies of cerebrovascular attack (cva) and specific ischemic regions of brain. methods: in this cross sectional study , ...

objective: the results of the previous studies on the correlation between plasma levels of homocysteine (hcy) and ischemic stroke have been controversial. the aim of the present study is to investigate this correlation meticulously observing risk factors for the ischemic stroke as well as factors affecting the plasma levels of hcy. method: a case-control study was conducted between 2005-2006 wi...

background: massive ischemic stroke causes significant mortality and morbidity in stroke patients. the main treatments for massive ischemic stroke are recombinant tissue plasminogen activator (rtpa), craniotomy, and endovascular interventions. due to destructive  effects  of   bradykinin  on  the  nervous system in ischemic stroke, it seems reasonable that using noscapine as a bradykinin antago...

introduction: the therapeutic potential of anandamide (aea) for the neurological disorders may be negatively affected by its short half-life or poor solubility. the superior properties of carbon nanotubes (cnts) for controlled drug delivery, prompted us to design aea-cnts complex and assess its effect in in vitro model of ischemic stroke. methods: in this experimental study, a multi-walled cnts...

cerebrovascular attack (cva) and transient ischemic attack (tia) are major causes of emergency department visits around the globe. a significant number of these patients may experience repeat attacks if left untreated. several risk stratifying scoring systems have been developed in recent years to point out the high risk patients. abcd 2 is based on age, blood pressure, clinical status, diabete...

a number of evidences suggest that during ischemic stroke, serum iron and hemoglobin (hb) levels are changed. yet, there are few reports in the literature related to this issue and resolution of this mechanism requires further experiments. the aim of the present study was to investigate the potential role of serum iron and hemoglobin levels as a  biomarker in diagnosis of acute ischemic stroke....

cerebrovascular accidents rank first in the frequency and importance among all neurological disease. although a number of studies had shown increased level of the high sensitive c-reactive protein (hs-crp) in patients with ischemic stroke, the association of increased hs-crp with various type of stroke especially the assessment hs-crp level in ischemic and hemorrhagic stroke have not been inves...

ischemic stroke accounts for about 87 percent of all cases. it occurs as a result of an obstruction within a vessel of the brain and sudden loss of blood circulation to the corresponding area resulting in the loss of brain function. it is caused by thrombotic or embolic occlusion of an artery and is more common than hemorrhagic stroke. we know that most of the injuries after an acute ischemic s...