With the continued expansion of corporate information systems and the increasing use of networks, information security management (ISM) has become more important than ever. However, few empirical studies have examined the effects of firms’ internal and external factors on their ISM processes. This study investigates the role of Need Pull and Technology Push on the ISM process, and examines the ...

OBJECTIVES The interferon (IFN) signature (IS) in patients with systemic lupus erythematosus (SLE) includes over 100 genes induced by type I IFN pathway activation. We developed a method to quantify the IS using three genes-the IS metric (ISM)-and characterised the clinical characteristics of patients with SLE with different ISM status from multiple clinical trials. METHODS Blood microarray e...

BACKGROUND Because of the development of resistance in trypanosomes to trypanocidal drugs, the livelihood of millions of livestock keepers in sub-Saharan Africa is threatened now more than ever. The existing compounds have become virtually useless and pharmaceutical companies are not keen on investing in the development of new trypanocides. We may have found a breakthrough in the treatment of r...

In this paper, a new approach for estimating the number of wideband sources is proposed which is based on RSS or ISM algorithms. Numerical results show that the MDL-based and EIT-based proposed algorithm havea much better detection performance than that in EGM and AIC cases for small differences between the incident angles of sources. In addition, for similar conditions, RSS algorithm offers hi...

In a companion paper, the authors provide the development and description of the Integrated Systems Model (ISM). In this article, they describe 14 general implications of the ISM for continuing medical education (CME). They discuss how applying the ISM would change CME by describing (1) how CME and the larger health care environment would be restructured if they were based on the ISM and (2) ho...

Isometamidium Chloride (ISM) is one of the principal drugs used to counteract Trypanosoma congolense infection in livestock, both as a prophylactic as well as a curative treatment. However, numerous cases of ISM resistance have been reported in different African regions, representing a significant constraint in the battle against Animal African Trypanosomiasis. In order to identify genetic sign...