BACKGROUND Hepatitis C virus (HCV) affects an estimated number of people between 130 million and 210 million worldwide. In the next few years, the Italian National Health Service will face a growing trend of patients requiring HCV antiviral treatments. The aim of the analysis was to estimate the time horizon in which it would be possible to treat HCV-infected patients and the related direct med...

OBJECTIVES The aim of this study was to review the history of health technology assessment (HTA) in Italy. METHODS Founded in 1978, the Italian National Health Service (NHS) has been strongly regionalized mainly after a constitutional reform, which started a devolution process. HTA started in the 1980s at the National Institute of Health and in a few University Hospitals, with a focus on big ...

This study shows a significant association between the number of macrolide prescriptions reimbursed by the Italian National Health Service and resistance of Streptococcus pyogenes to erythromycin in children from a region in northern Italy with high prevalence of erythromycin resistance. Recent prescription of a macrolide (especially azithromycin) is a predictor of erythromycin resistance, as w...

In the past decade, the G8 played an important part in the establishment or support of global health initiatives that are at risk today of becoming part of the problem rather than the solution for granting health coverage to disadvantaged populations. The fragmentation of fi nancing for global health and increased transaction costs contrast with the need for effi cient and eff ective health sys...

The design of the entire system was carried out by the National Center for Informatics in the Public Administration of Italy (DigitPA), followed by efforts for the implementation and testing of the service. The DigitPA has given the Italian National Research Council (CNR), and in particular the Institute of Information Science and Technologies at the CNR (ISTI), the task of running tests on pro...