Despite the fundamental function of neutrophils (polymorphonuclear leukocytes (PMNs)) in innate immunity, their role in Escherichia coli K1 (EC-K1) -induced meningitis is unexplored. Here we show that PMN-depleted mice are resistant to EC-K1 (RS218) meningitis. EC-K1 survives and multiplies in PMNs for which outer membrane protein ...

We show that there exist knots K ⊂ S with g(E(K)) = 2 and g(E(K#K#K)) = 6. Together with [5, Theorem 1.5], this proves existence of counterexamples to Morimoto’s Conjecture [10]. This is a special case of [6]. Let Ki (i = 1, 2) be knots in the 3-sphere S, and let K1#K2 be their connected sum. We use the notation t(·), E(·), and g(·) to denote tunnel number, exterior, and Heegaard genus respecti...

A (k1, k2)-outdegree-splitting of a digraph D is a partition (V1, V2) of its vertex set such that D[V1] and D[V2] have minimum outdegree at least k1 and k2, respectively. We show that there exists a minimum function fT such that every tournament of minimum outdegree at least fT (k1, k2) has a (k1, k2)outdegree-splitting, and fT (k1, k2) ≤ k 1/2+3k1/2+k2+1. We also show a polynomial-time algorit...

Let K (K = K2 whose residue field is K1 whose residue field is K0, see the notation in section 1 of Part I) be a two-dimensional local field of equal characteristic. Thus K2 is isomorphic to the Laurent series field K1((t2)) over K1. It is convenient to think of elements of K2 as (formal) loops over K1. Even in the case where char (K1) = 0, it is still convenient to think of elements of K1 as (...

Let 1 → (K, K1) → (G, NG(K1)) → (Q, Q1) → 1 be a short exact sequence of pairs of finitely generated groups with K strongly hyperbolic relative to the subgroup K1. Let relative hyperbolic boundary of K with respect to K1 contains atleast three distinct parabolic end points and for all g ∈ G there exists k ∈ K such that gK1g −1 = kK1k , then we prove that there exists a quasi-isometric section s...

Expression of the K1 gene of human herpesvirus 8 activates nuclear factor-kappaB and induces lymph node hyperplasia and lymphomas in transgenic mice. To further delineate its role in cell survival, we determined whether K1 altered apoptosis of lymphoma cells. K1 protein is expressed in Kaposi sarcoma and primary effusion lymphoma. We retrovirally transfected BJAB lymphoma, THP-1, U937, and Kapo...

Background: The critical role of interleukin-7 (IL-7) in homeostatic proliferation and T cell survival has made it a promising cytokine for the treatment of various clinical conditions, especially those associated with lymphopenia. Methods: In the present study we expressed recombinant human interleukin-7 (rhIL-7) in Chinese hamster ovary (CHO)-K1 cells. CHO-K1 cells were stably transfected ...

This paper presents an analysis and control of chaos in the boost converter controlled with zero average dynamics, fixed-point induced control, time-delayed autosynchronization techniques. First, existence is demonstrated numerically when positive Lyapunov exponents are found system, for a range from k1=−0.26 to k1=0.4387, k2=0.5. Additionally, also k1=−0.435 k1=0.26, k2=−0.5. Subsequently, fix...