PURPOSE OF REVIEW Topical corticosteroid use in the setting of infectious keratitis has been a controversial issue. The aim of this review is to provide an update on the evidence for use of topical corticosteroids in addition to antibiotics in bacterial keratitis. RECENT FINDINGS Judicious use of steroids is postulated to limit the inflammatory component of bacterial keratitis, but can theore...

PURPOSE To report the profile of microbial keratitis occurring after corneal collagen cross-linking (CXL) in keratoconus patients. METHODS A retrospective analysis of 2350 patients (1715 conventional CXL, 310 transepithelial CXL, and 325 accelerated CXL) over 7 years (from January 2007 to January 2014) of progressive keratoconus, who underwent CXL at a tertiary eye care centre, was performed....

For the purpose of determining the effect of levamisole on cell-mediated immunity of patients with herpetic stromal keratitis, the response of peripheral lymphocytes to three mitogens (PHA, Con A and PWM) was examined in a total of 19 cases of herpetic stromal keratitis (16 effective cases) including 12 patients undergoing levamisole administration. As controls, a similar study was made on 35 h...

PURPOSE To identify the most common etiologies of corneal disease and the risk factors associated with worse visual outcomes in Changsha, Hunan, located in southern China. METHODS This observational, cross-sectional study evaluated 100 consecutive patients seen at the cornea clinic of The Second Xiangya Hospital of Central South University. Ocular history, demographic information, and ocular ...

CONTEXT Fungal keratitis is a potentially blinding condition that is rarely seen with contact lens wear. OBJECTIVE To describe a nationwide outbreak of fungal keratitis caused by Fusarium species among contact lens wearers in Singapore. DESIGN, SETTING, AND PATIENTS Nationwide, hospital-based case series. All cases of fungal keratitis among contact lens wearers in all ophthalmology departme...

PURPOSE OF REVIEW Throughout the world, fungal keratitis is a leading cause of ocular morbidity. The purpose of this review is to discuss the recently published literature in relation to the epidemiology, etiology, diagnosis, and therapy of fungal keratitis. RECENT FINDINGS Globally, the incidence of keratomycoses and systemic mycoses is rising. Current therapies are often ineffective. Ongoin...

PURPOSE To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. METHODS Case report and literature review. RESULTS A 62-year-old man with a history of mixed cryoglobulinemia developed an episode of necrotizing scleritis and peripheral ulcerative keratitis one month after...

PURPOSE To describe a patient with Thygeson's superficial punctate keratitis successfully treated with long-term cyclosporin A. CASE PRESENTATION A 15-year-old boy presented with long-term ocular symptoms of foreign body sensation, burning, irritation, tearing, and transient photophobia. One year's treatment with steroidal agents had led to only partial improvement. Clinical and laboratory ev...