Kindler et al. (1956) reported that a strain of Clostridium parabotulinum type A synthesized large quantities of toxin in a medium where cell multiplication was inhibited by high concentrations of penicillin. This interpretation of synthesis de novo of protein was based on the observations that the toxicity of the extracellular fluids increased in the absence of cell multiplication. It is a wel...

In this paper, we prove an almost-optimal hardness for Max k-CSPR based on Khot’s Unique Games Conjecture (UGC). In Max k-CSPR, we are given a set of predicates each of which depends on exactly k variables. Each variable can take any value from 1, 2, . . . , R. The goal is to find an assignment to variables that maximizes the number of satisfied predicates. Assuming the Unique Games Conjecture,...

Background. Kindler epidermolysis bullosa is orphan, autosomal recessive disease and it one of the variants congenital bullosa. Its severe course characterized by high risk multifactorial malnutrition, chronic inflammation due to recurrent secondary skin infections, also bone metabolism disorders, what can lead disorders in physical development puberty children. However, effect on patients’ rem...

A.N. Andreyev, S. Antalic, D. Ackermann, S. Franchoo, F. P. Heßberger, S. Hofmann, M. Huyse, I. Kojouharov, B. Kindler, P. Kuusiniemi, S. R. Lesher, B. Lommel, R. Mann, G. Münzenberg, K. Nishio, R.D. Page, J. Ressler, B. Streicher, B. Sulignano, P. Van Duppen, and D. Wiseman TRIUMF, 4004 Wesbrook Mall, Vancouver BC, Canada, V6T 2A3; Department of Nuclear Physics, Comenius University, Bratislava...