background:  new discoveries about the pathophysiology changed the concept that all forms of osteoarthritis are alike; this lead to the delineation of different phenotypes such as age, trauma or obese related forms. we aim to compare soluble mediator profiles in primary knee and posttraumatic wrist osteoarthritis. based on the general faster progression rate of wrist osteoarthritis, we hypothes...

background: knee extension contracture is a disabling complication after fractures around the knee. in this study we aimed to study factors influencing the outcomes of quadricepsplasty for the treatment of traumatic knee extension contracture. we hypothesized that there is no factor influencing the final range of knee motion.methods: in this retrospective study, we included 64 patients who unde...

introduction: reverse transcriptase-polymerase chain reaction (rt-pcr) assay is a useful tool for the detection of fusion transcript resulting from specific chromosomal translocation of the leukemia cells. a specific chromosomal abnormality, the philadelphia chromosome (ph), is present in 90% to 95% of cml patients.the aberration results from a reciprocal translocation between chromosome 9 and ...

splenogonadal fusion is a rare congenital malformation whereby the splenic tissue is found attached or surrounded by the testis, and presents in both continuous and discontinuous forms. splenogonadal fusion may be misinterpreted as a primary malignant testicular or an adenomatoid tumor. knowledge about the existence of such an entity is essential in order to preserve the testis during surgical ...

conclusions both l-prp and l-prf could be used to effectively promote the healing of articular cartilage defects of the knee. results mean macroscopic scores of the treated defects were higher than the controls at all sampling times with significant differences (p < 0.05) observed between l-prf treated and control defects (10.13 vs. 8.37) and l-prp treated and control defects (10 vs. 8.5) at 4 ...

background & importance: spinal deformity is one of the most common disorders among the vertebral diseases that results from unnatural curvatures of spine, such as scoliosis and kyphosis. spinal fusion surgery used most commonly to treat certain types of spinal deformity. here in, we report the efficacy of posterior spinal fusion accompanied by instrumentation in patients with the limitations o...

With increasing life expectancy, the demand for preservation of native articular cartilage is increasing to delay joint arthroplasties. In the knee, there are many different strategies to preserve the articular cartilage including but not limited to corrective osteotomies, chondral injury restoration, intraarticular injection of cells or growth factors(PRP). However, One of the most important s...

Background: The Philadelphia chromosome (Ph) characterized by t (9; 22) (q34; q11.2) is a reciprocal translocation giving rise to a chimeric BCR-ABL fusion gene. Incidence of Ph chromosome is over 98% in Patients with Chronic Myeloid Leukemia (CML) and around 20% in acute lymphoblastic leukemia (ALL). The finding of this fusion gene is essential for diagnosis of CML by detection of various fusi...