AIMS To investigate the effect of tissue preparation on immunostaining and to establish whether there is a standard tissue preparation schedule that allows optimal demonstration of all antigens. METHODS Blocks of tonsil were subjected to variations to a standard fixation, processing, and section preparation schedule. The sections were stained with five antibodies-L26 (CD20), UCHL1 (CD45RO), C...

Social enterprises have attracted increased attention from both researchers and practitioners around the world. In social enterprise context, scaling impact is considered main currency or key performance metric. Two overarching strategies are organizational growth strategy ecosystem strategy. However, to date, little cumulative knowledge exists on these two strategies. To address this issue, ar...

2-Chlorodeoxyadenosine (2-CdA) yields high complete remission (CR) rates in patients with hairy cell leukemia (HCL). In an effort to detect minimal residual disease, we studied two B-lineage antibodies, L26 and MB2, and a T-lineage antibody, UCHL-1, in fixed marrow core biopsies from 34 patients with HCL before and after 2-CdA. Before therapy, hairy cells exhibited intense cytoplasmic membrane ...

We study how to design an optimal government loan program for risky R&D projects with positive externalities. With adverse selection, the contract involves a high interest rate but nearly zero cofinancing by entrepreneur. This contrasts sharply observed schemes. selection and moral hazard, allowing two levels of effort entrepreneur, policy consists menu at most contracts, one self-financing...

The COVID-19 pandemic has exposed the economy to immense distress, ruptured multiple systems and left out of breath. present study made an exploratory attempt unleash business-related issues faced by textile entrepreneurs India (Punjab) due COVID-19. data were collected from 123 industry in Punjab. Factor analysis regression have been used for purpose analysis. It was found that major include r...

Throughout history, societies have been beset by disasters that took them surprise, often with widespread and devastating consequences. When crops, animals, or people began dying unusual frequency, especially when the causes were not observable, failed to respond, responded very slowly, in surprisingly misdirected ways. In this essay, we focus on role of leadership addressing failing address su...

We implement a lab-in-the-field experiment with 334 Turkish loan officers to document gender discrimination in small business lending and unpack mechanisms. Officers review multiple real-life applications which we randomize applicant gender. While unconditional approval rates are the same, 26 percent more likely require guarantor when present same application as coming from female instead of ma...

L’objectif de ce travail est d’identifier les conditions d’émergence des projets entrepreneuriaux hybrides. Les hybrides étudiés intègrent une diversité d’acteurs et logiques en centrant leur activité sur la création valeur sociale grâce à ressources mixtes. L’hybridité d’un projet implique présence irrémédiable tensions organisationnelles dues aux parfois contradictoires traversant le projet. ...

The purpose of this paper is to examine the existence of cross-level moderating effects between national appropriability conditions, individual level predictors and entrepreneurial growth aspirations. We test a multi-level model that connects the determinants of strategic resource allocation decisions at the individual level with the strength of the intellectual property rights regime at the na...