Background Spironolactone (SPL) is a reversible mineralocorticoid receptor (MR) and androgen (AR) antagonist which attracts pharmacotherapeutic interest not only because of its beneficial effects in heart failure but also the pathogenetic roles MR AR activities neuropsychiatric diseases. Recently, rapid-onset SPL have been documented case series women with fibromyalgia syndrome (FMS). To reaffi...

International tourism and its related businesses have considerably increased recently. Due to this expansion, tourism employees must be able to communicate appropriately, and effective ESP programs need to be administered accordingly. Many studies have been conducted on current ESP courses for tourism; however, major problems still remain in designing ESP courses to satisfy L2 learners’ needs, ...