background: langerhans cells are important in the pathogenesis of leprosy.  a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions.   objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy.   methods: an immunohistochemical staining for s100 ...

Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...

this study was conducted to determine the properties of islets of langerhans in pancreas of adult and immature, male and female maquee sheep. for this purpose, 20 samples of pancreas were used equally for each male and female, immature and adult animals. paraffin sections that they were stained by h&e; method were used for mean distribution and dimension of langerhans islets, and maldonado stai...

the final treatment for diabetes is transplantation of islets of langerhans. one of the new proposed methods for immunological preservation of transplanted cells is coating of cell surface by polyethylene glycol. in this study, the surface of islets of langerhans was coated by cyanuric chloride activated methoxy polyethylene glycol. the effect of polymer coating, at two different reaction times...

Langerhans cell histiocytosis includes a broad spectrum of clinical diseases resulted from proliferation and tissue infiltration of differentiated langerhans cells. This term includes Letterer-siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma and congenital reticulohistiocytosis that are more common in children than adults. This entity has recently been classified into restr...

results there was a significant difference in prevalence of ebv presence between patients and controls. the ebv was found by rt-pcr in 19 (63.33%) out of 30 patients and only in eight (26.7%) of 30 control samples. the p = 0.004, was calculated using chi-square test (or: 4.75; 95% ci: 1.58 ‒ 14.25). conclusions our study is the first investigation performed on patients with lch and its possible...

The functional activity of skin cells derived from an infant who died of multisystem Langerhans cell histiocytosis (LCH) was examined. Involved and non-involved skin was obtained at postmortem examination within three hours of death; normal epidermal Langerhans cells and 'LCH cells' were separated by means of dispase digestion. The functional activity of different populations of CD1a positive c...

objective(s): ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. the central effects including gh secretion, food intake, and energy homeostasis are partly mediated by kiss1- kissr signaling pathway. ghrelin and its receptor are also expressed in the pancreatic islets. ghrelin is one of the key metabolic factors controlling insulin secretion from t...