The risk factors affecting the survival rates of laryngeal carcinoma are not well understood. In this study, we investigated the expression status of mutS homolog 2 (MSH2) and mutL homolog 1 (MLH1) and examined the relationship between these two molecules and overall survival rates in laryngeal cancer. We also explored the potential reason for the altered expression of these two genes. Using re...

Synaptic transmission at the vocal synapse, the laryngeal neuromuscular junction, of Xenopus /aevk has been shown to be regulated by long-term changes in circulating estrogen. In females, high levels of circulating estrogen also accompany gonadotropin-induced ovulation and oviposition and the switch from sexually unreceptive to receptive states, including changes in vocal behaviors (ticking to ...

BACKGROUND Diffusion-weighted magnetic resonance imaging (DWI) has been introduced in head and neck cancers. Due to limitations in the performance of laryngeal DWI, including the complex anatomical structure of the larynx leading to susceptibility effects, the value of DWI in differentiating benign from malignant laryngeal lesions has largely been ignored. We assessed whether a threshold for th...

Gonadal differentiation, the onset of androgen-stimulated laryngeal growth and the genesis of a sex difference in laryngeal innervation, all temporally coincide with thyroid hormone (TH)-induced metamorphosis in Xenopus laevis. To explore the role TH plays in the ontogeny of the Xenopus androgen-sensitive vocal neuromuscular system, we examined gonadal and laryngeal development in tadpoles in w...

OBJECTIVES/HYPOTHESIS Assess long-term patient satisfaction with conventional thyroidectomy scars and the impact of thyroidectomy scars on patient quality of life. STUDY DESIGN Validated survey administration and retrospective review of clinical and demographic data. METHODS Patients who underwent conventional thyroidectomy through years 2000 to 2010 were identified and administered the val...

OBJECTIVES To compare the scar outcome of video-assisted parathyroidectomy (VAP) with traditional bilateral cervical exploration (BCE) using previously validated scar assessment scales, and to examine the feasibility of introducing VAP into a general otolaryngology-head and neck practice. DESIGN A retrospective review of medical records from a prospectively obtained database of patients and l...

primary non-hodgkin lymphoma of the larynx is rare, accounting for less than 1% of all laryngeal neoplasms. fewer than 100 cases have been reported in the literatureand to our knowledge this may be the first reported case of laryngeal non hodgkin lymphoma presented with hoarseness, aortic aneurysm, hepatitis b and skin rashes.

mucoepidermoid carcinoma is a neoplasm of salivary gland origin, and its laryngeal occurrence is extremely rare. this malignant tumor is composed of two distinct cell types, the epidermoid and mucus cells. prognosis is largely dependent on the histologic pattern. in this report, an extremely rare laryngeal cancer and its clinicopathologic features are described.

This case describes the development of laryngeal chondronecrosis after use of the laryngeal mask airway (LMA). A 69-year-old male with prior laryngeal irradiation underwent total knee replacement with general anesthesia via LMA. Postoperatively, he developed laryngeal chondronecrosis, bilateral vocal fold immobility, and aspiration, necessitating tracheostomy and gastrostomy placement. He impro...

CE Dysfunction of the recurrent laryngeal nerves causes laryngeal paralysis in dogs and cats. Paralysis of the cricoarytenoideus dorsalis muscle results in an inability to abduct the arytenoid cartilages during inspiration.The resulting cross-sectional area of the glottis is inadequate for normal respiration.The most common clinical signs of laryngeal paralysis in dogs and cats are stridor, exe...