Background. Patients with aortic stenosis have a period of compensated left ventricular hypertrophy but may eventually develop congestive heart failure. Previous experimental studies showed either normal myocardial contractility in mild short-term pressure overload or myocardial dysfunction with severe pressure overload. Transition from compensated left ventricular hypertrophy to myocardial dys...

Normal or near-normal exercise capacity has been thought to reflect normal left ventricular function. Many compensatory mechanisms could preserve exercise capacity in patients with severe left ventricular dysfunction. We evaluated exercise capacity using a treadmill exercise test in 26 patients with severe left ventricular dysfunction defined by a left ventricular ejection fraction of 30% or le...

BACKGROUND Patients with aortic stenosis have a period of compensated left ventricular hypertrophy but may eventually develop congestive heart failure. Previous experimental studies showed either normal myocardial contractility in mild short-term pressure overload or myocardial dysfunction with severe pressure overload. Transition from compensated left ventricular hypertrophy to myocardial dysf...

The evolution of left ventricular dysfunction in 36 patients with coronary artery disease and no interim surgical intervention was studied over a mean interval of 26 months (range 6-71 months). The ejection fraction decreased 0.08 (p < 0.001) on the average in patients with coronary artery disease progression. However, progression of coronary artery disease was not accompanied by a decrease in ...

2011;58;2698-2699 J. Am. Coll. Cardiol. Carlo G. Tocchetti, Carmela Coppola, Claudio Arra, and Nicola Maurea Early Identification of Left Ventricular Dysfunction Induced by Trastuzumab This information is current as of December 9, 2011 http://content.onlinejacc.org/cgi/content/full/58/25/2698-a located on the World Wide Web at: The online version of this article, along with updated information ...

To determine the effects of chronic nonocclusive coronary constriction on cardiac hemodynamics, structural integrity, and contractile protein enzyme activity, the left coronary artery was narrowed in rats, and measurements of ventricular performance, magnitude, and distribution of tissue damage and myofibrillar Mg2+ and Ca2+ myosin ATPase activities were evaluated 1 month later. In the presence...

background: dextrocardia is a congenital anomaly, which may have coexistent coronary artery disease (cad), arrhythmias and conventional indications for device therapy. however, the implantation of transvenous leads can be technically challenging and the approach needs to be tailored to the patient&apos;s individual anatomy. case presentation: a 54-year-old male with dextrocardia situs inversus ...

To assess ventricular function in patients who have undergone cardiac transplantation, 247 radionuclide ventriculograms were performed on 94 patients. During the first three days after transplantation, 19% demonstrated left ventricular dysfunction and 41% showed isolated right ventricular dysfunction. In 95 cases, radionuclide ventriculography was performed within 24 hr of myocardial biopsy. A ...