The treatment of medical conditions with cannabis and cannabinoid compounds is advancing. Although there are numerous reports related to the genetic variations of the cannabinoid receptor, a lack of studies that examine the relationship between other pharmacogenetic markers and health outcomes currently exists. Herein, we advocate for the legalization of marijuana in the United States in order ...

I applaud the members of the Senate Judicial Proceedings Committee for holding this hearing regarding Senate Bill 757, which seeks to shield qualified patients who use cannabis therapeutically with a doctorʹs recommendation from criminal prosecution. The physician-supervised use of medicinal cannabis is a scientific and public health issue. It should not be held hostage by the socalled “war on ...

The Dutch depenalization and subsequent de facto legalization of cannabis since 1976 is used here to highlight the strengths and limitations of reasoning by analogy as a guide for projecting the effects of relaxing drug prohibitions. While the Dutch case and other analogies have flaws, they appear to converge in suggesting that reductions in criminal penalties have limited effects on drug use-a...

CONTEXT In 2012, Washington State and Colorado legalized the recreational use of marijuana, and Uruguay, beginning in 2014, will become the first country to legalize the sale and distribution of marijuana. The challenge facing policymakers and public health advocates is reducing the harms of an ineffective, costly, and discriminatory "war on drugs" while preventing another public health catastr...

Changes in the legality of marijuana for medicinal use and further legalization recreational have brought about renewed interest properties cannabis plant. Cannabidiol (CBD), a derivative plant, has emerged as widely available panacea. The purpose this review is to discuss differences active ingredients plant well mechanisms by which CBD may provide benefit. In addition, evidence pain managemen...