Introduction Visceral and cutaneous leishmaniasis are endemic in the Maltese islands. Leishmania infantum has been cultured from humans, dogs and the sandfly PhZebotomus perniciosus (GRADONI et al., 1991). Since 1955 the incidence of leishmaniasis has been about 10 local new cases per year compared with about 150 cases per year in the immediate post-war period (CACHIA & FENECH, 1964; Ministry o...

To the Editor: In Afghanistan, most cutaneous leishmaniasis cases are caused by Leishmania tropica, which is transmitted anthroponotical-ly by the sandfly Phlebotomus sergen-ti (1). Cutaneous leishmaniasis can have devastating effects on local communities because of its clinical symptoms , i.e., large, multiple, or both, disfiguring lesions, that can lead to social ostracism of affected persons...

BACKGROUND & OBJECTIVES The recently recognized endemic focus of leishmaniasis in Satluj river valley in Himachal Pradesh (India) lies in north-western Himalayas (30 degrees N, 70 degrees E). This endemic focus of leishmaniasis appears peculiar where localized cutaneous leishmaniasis (LCL) co-exists with visceral leishmaniasis (VL), and Leishmania donovani is predominant pathogen for LCL wherea...

Leishmaniasis is a neglected tropical disease caused by a protozoan parasite of the genus Leishmania. Visceral leishmaniasis is the most severe type and is transmitted by the phlebotomine sandflies of genera Lutzomyia (New World) or Phlebotomus (Old World) to human and other vertebrates. Leishmaniasis is widespread in developing countries with current mortality rate of 50 thousand deaths per ye...

AIM There are six main types of granulomas in dermatopathology. The aim is to present and describe a seventh pattern of granuloma that we came across while studying biopsies of cutaneous leishmaniasis. MATERIALS AND METHODS We investigated 17 cases of cutaneous leishmaniasis. A granulomatous response was identified in 14 of them. The features that were common to all of them were noted. These ...

UNLABELLED Leishmaniasis infection may involve destruction of nasal tissues resulting in lacrimal drainage system alteration. PURPOSE To evaluate the frequency of lacrimal excretory system sequelae in patients treated for leishmaniasis. METHODS Forty-five leishmaniasis-treated patients (90 nasolacrimal ducts) were submitted to lacrimal excretory system evaluation. All were evaluated by Jone...

Interleukin 17 (IL-17) plays a critical role in inflammation and autoimmunity. Very little is known about IL-17 in protozoa infection. Here, we show that lymphocytes obtained from patients with mucosal leishmaniasis and cutaneous leishmaniasis produce higher levels of IL-17 than do lymphocytes obtained from uninfected control subjects (P<.01). There was a tendency for tissue obtained from patie...

Leishmaniasis is a protozoan parasitic disease endemic to the tropical and subtropical regions of the world, with three major clinical forms, self-healing cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). Drug treatments are expensive and often result in the development of drug resistance. No vaccine is available against leishmaniasis. Subunit Lei...

Chagas disease and leishmaniasis are vector-borne infectious diseases affecting both humans animals. These neglected tropical can be fatal if not treated. Hundreds to thousands of new disease...

Forty-one naturally infected dogs with visceral leishmaniasis from an urban area of Corumbá (Mato Grosso do Sul-BRAZIL) were studied and three types of lung involvement due to visceral leishmaniasis were characterized; a cellular, a cellular-fibrotic and a fibrotic type. These types seem to represent a sequential evolutive proce'as. Visceral leishmaniasis frequently causes an interstitial pneu ...