OBJECTIVES The purpose of the study was to evaluate the relationship between elevated lung/heart ratio (LHR) and transient ischemic dilation (TID) after stress thallium-201 myocardial perfusion imaging and to provide further insight into the mechanism of cavity dilation. BACKGROUND Because both LHR and TID have been identified as adjunctive markers of severe coronary disease they should be fo...

OBJECTIVES To compare prediction of postnatal survival in isolated diaphragmatic hernia by prenatal two-dimensional (2D) versus three-dimensional (3D) sonographic assessment of the contralateral lung. METHODS The lung area to head circumference ratio (LHR) of the contralateral lung was measured and expressed as a percentage of the normal mean for gestation (O/E) in 47 fetuses with isolated di...

The aim of this study was to investigate the effects of different Luteinizing hormone (LH) and steroid hormones levels on LH receptor (LHR) expression in the hippocampal cells. Rats (24 males and 24 females) were assigned to four groups: one control and three experimental [gonadectomy (GDX), gonadectomy + gonadotropin releasing hormone analogue (GDX+GnRHa) and GDX+GnRHa+estradiol (E2) or testos...

Background: We investigated whether the lungheart ratio parameter (LHR) can be used to identify the optimum cut off frequency for Butterworth filter in 99mTc myocardial SPECT imaging. Materials and Methods: This study involved a cardiac phantom system consisting of cardiac insert in which 1.10 cm cold defect was inserted into its myocardium wall and filled with 4.0 μCi/ml (0.148 MBq/ml...

In this report we investigate the limits of routing according to leftor right-hand rule (LHR). Using LHR, a node upon receipt of a message will forward to the neighbour that sits next in counter-clockwise order in the network graph. When used to recover from greedy routing failures, LHR guarantees success if implemented over planar graphs. This is often referred to as face or geographic routing...

OBJECTIVE To compare laparoscopic hepatic resection (LHR) with open hepatic resection (OHR) for benign and malignant tumors. DATA SOURCES MEDLINE, CENTRAL, and EMBASE databases were searched for relevant studies published between January 1, 1998, and May 1, 2009. STUDY SELECTION Studies clearly documenting a comparison of LHR with OHR for benign and malignant neoplasms were selected. DATA...

The uvr mutations of Escherichia coli K-12 decrease the ability of cells to survive ultraviolet light (UV), to excise pyrimidine dimers from their deoxyribonucleic acid and to reactivate bacteriophage exposed to UV. The rec mutations decrease the ability of the cells to survive UV and to undergo genetic recombination. Certain rec mutations, including recA1, rec-12, recA13, and rec-56, are neces...

The studies summarized here clearly show that the phosphorylation of one or more serine residues (S635, S639, S649 and/or S652) present in the C-terminal tail of the LHR is necessary, but not sufficient, for the agonist-induced uncoupling of the LHR from adenylate cyclase and for the endocytosis of the agonist-receptor complex. Simultaneous mutation of these four serines to alanines decreases t...

The cloning of the cDNAs for the rat (1) and porcine (2) LH receptor (LHR) in 1989 provided us with new experimental tools that resulted in a tremendous explosion in our knowledge of the structure and functions of the LHR as well as the closely related FSH and TSH receptors (reviewed in Refs. 3–7). Some of the most important recent advances in this area include 1) the discovery that naturally o...

Our previous studies demonstrated that the histone deacetylase inhibitor, trichostatin A (TSA), induces derepression of the human luteinizing hormone receptor (LHR) gene by de-recruitment of the pRB homologue p107 repressor from the promoter in JAR and MCF-7 cancer cells. TSA initiates a mechanism whereby the phosphatidylinositol 3-kinase/protein kinase zeta (PKCzeta) cascade phosphorylates Sp1...