The increased cancer risk associated with hormone therapies has encouraged many women to seek non-hormonal alternatives including botanical supplements such as hops (Humulus lupulus) and licorice (Glycyrrhiza spec.) to manage menopausal symptoms. Previous studies have shown estrogenic properties for hops, likely due to the presence of 8-prenylnarigenin, and chemopreventive effects mainly attrib...

abstract background and aim: oral infections and dental caries are considered as two serious public health problems, which inflict a costly burden on health care services worldwide, especially in the developing countries. the aim of this study was to evaluate the antibacterial activity of iranian licorice aqueous root extract on lactobacillus acidophilus in comparison with chlorhexidine. materi...

abstract prostate cancer is the second most common cancer in men after skin cancer.  throughout the years, medicinal plants, in some cases is the only treatment were considered. glycyrihiza glabra l. liquorice plant with the scientific name 'glycyrihiza glabra l.' which belongs to the family fabaceae, there are three species of perennial herbaceous plants in iran. root extract is wide...

Vasomotor hot flash is the most common and distressful complication of menopausal women. Its treatment is the most frequent clinical challenge. As a result, an effective and harmless therapy is needed. This double-blind controlled clinical trial was conducted to determine the effects of licorice roots on the relief and recurrence of hot flash in menopausal women referring to the healthcare cent...

     Licorice is obtained from Glycyrrhiza glabra (G. glabra) in Iran. Glycyrrhizin is the main constituent of G. glabra and has several pharmacological effects. It is hydrolyzed to glycyrrhetic acid (GA) in the intestine after oral administration. In this study, a novel HPLC method was used to determine the concentration of GA in rat plasma after oral administration ...

Natural compounds are considered treasures in biotechnology; however, the past, process of discovering bioactive is time consuming, and purification validation biofunctions biochemistry isolated from a medicinal herb tedious tasks. In this study, we developed an economical called biotransformation-guided (BGP), which applied to analyze licorice, traditional Chinese medicine widely used many the...

Many herbal medicines and compositions are clinically effective but challenged by its safety risks, i.e., aconitine (AC) from aconite species. The combined use of Radix glycyrrhizae (licorice) with Radix aconite L. effectively eliminates toxicity of the later while increasing efficacy. In this study, a boiling-stable 31-kDa protein (namely GP) was purified from licorice and self-assembled into ...