The relatively low levels of transfection that can be achieved by current gene delivery systems have limited the therapeutic utility of gene transfer. This is especially true for non-viral gene delivery systems, where the levels of gene expression achieved are usually well below the levels achieved by viral gene transfer systems. Previous work from our laboratory describes an enhanced dual prom...

Each year in the past three decades has seen hundreds of thousands of runners register to run a major marathon. Of those who attempt to race over the marathon distance of 26 miles and 385 yards (42.195 kilometers), more than two-fifths experience severe and performance-limiting depletion of physiologic carbohydrate reserves (a phenomenon known as 'hitting the wall'), and thousands drop out befo...

INTRODUCTION: Rapid urbanization and population expansion, coupled with sustained income growth and the emergence of an urban African middle class are triggering an increase in the consumption of animal protein in developing countries. The sustained increase in the consumption of animal proteins creates a host of new development opportunities to synergistically link smallholder livestock produc...

There are many approaches to computational simulation of turbulence. These include field computations based on Navier Stokes Equations, various forms of discrete simulation involving particles and vortices or vortex sheets, and phenomenological approaches such as large eddy simulation. Turbulence is striking because of the large range of scales encountered, which in computational terms means th...

7he undentanding qf whether and what kind of institutional rehabilitation is needed depmds (a) on the method used, and (b) on the objectives (values. goals etc.) (jf such analyses. TIe results 0/ such analyses qf dysJunctional or .functional element.5 depend on the .frame I!f refeunce. TIe hest methods used .for diagno.fi.5 are not very d/ective if the data are not intelpreted in a hroader fram...

In first explicating the notion of quantitative literature review for the social sciences, Glass (1976) argued that knowledge is not built from any individual study, but from the integration of findings from many studies. Individual studies do not so much yield knowledge as evidence with which knowledge can be built. Knowledge is socially constructed. To overemphasize a single study’s findings ...