Homocysteinemia is associated with cardiovascular and neuronal degenerative diseases. Deficiencies of the B vitamins lead to high homocysteine serum levels. Lentinus edodes (L. edodes) is also known as the Shiitake mushroom and may have beneficial effects on vascular and lipid metabolic diseases, including hypertension, homocysteinemia and lipidemia. In this study, we induced a homocysteinemia-...

BACKGROUND This study examined associations of annual glycemic variability and postprandial dysmetabolism with annual decline in estimated glomerular filtration rate (eGFR) in type 2 diabetic patients with different stages of nephropathy. METHODS Intrapersonal mean and coefficient of variation (CV) of HbA1c, fasting and postmeal concentrations of plasma glucose (FPG and PMPG, respectively) an...

to study the changes of serum uric acid level which is influenced by various factors including nutrition, race, socio-economic conditions age, sex, obesity and hyper lipidemia, a wide variety of survey appeared to be performed. for this study in six large provinces of iran out of 12,524 apparently healthy individuals a total of 2,744 persons of both sexes (1,439 females, 1,305 males) were selec...

objective: this research was conducted to evaluate the prevalence of diabetic retinopathy (dr) in patients who were unaware of their eye condition. materials and methods: a descriptive cross-sectional study was performed in a 12-month period on patients who were referred to meybod imam sadegh diabetes center. 152 patients who had no eye complaint were selected. pupil dilation was created by cyc...

BACKGROUND The importance of exchanging sucrose for artificial sweeteners on risk factors for developing diabetes and cardiovascular diseases is not yet clear. OBJECTIVE To investigate the effects of a diet high in sucrose versus a diet high in artificial sweeteners on fasting and postprandial metabolic profiles after 10 weeks. DESIGN Healthy overweight subjects were randomised to consume d...

OBJECTIVE During the last decade cardiovascular risk factors and endothelial dysfunction have been shown to be present early in life in women with Polycystic Ovary Syndrome (PCOS). The aim of the present study was a global assessment of abnormalities in the arterial bed of young women with PCOS by non-invasive, reproducible methods. DESIGN 27 women with PCOS and 27 control women of comparable...

Objective: This investigation was undertaken to determine whether a grape seed extract (GSE) that is rich in mono-, oligoand polymeric polyphenols would modify postprandial oxidative stress and inflammation in individuals with the metabolic syndrome (MetS). Background: MetS is known to be associated with impaired glucose tolerance and poor glycemic control. Consumption of a meal high in readily...

The natural course of early atherogenesis is not well established. The current prospective survey was designed to monitor 5-year changes in carotid atherosclerosis in a large, stratified random sample of the general population using high-resolution duplex ultrasound (Bruneck Study). Incidence rates of carotid atherosclerosis ranged from near zero to 184 per 1000 person-years. Most atherosclerot...

BACKGROUND Pure arm monoparesis is an uncommon presentation of stroke. Localization of the lesions is variable, including cortical, subcortical or deep brain infarcts. No particular risk factors or unifying mechanisms have been clearly identified. METHODS Seven patients (5 women, 2 men) presented with isolated arm weakness and brain magnetic resonance imaging (MRI) documented an infarct in th...

Objective(s): Metabolic syndrome is a multiplex risk factor for diabetes and cardiovascular disease. Since some dietary fats such as mono-unsaturated fatty acids (MUFA) modify metabolic syndrome components the aim of the present study was to evaluate  the preventive effects of mixture, kernel and hull oils of wild pistachio (WP) (Pistacia atlantica mutica) as good sources of MUFA on different f...