LiR – Librarian in Residence, so lautet der Titel des Residenzprogramms für Mitarbeitende deutschen Bibliotheken und Informationseinrichtungen, das jährlich von BI-International ausgeschrieben wird ein bis zwei Spezialist*innen zu einem definierten Thema Fachaufenthalt ins Ausland entsendet. Nach Anfängen 2008-2018 den USA fand LiR-Programm Niederlanden statt seit Beginn Partnerland-Initiative ...

The molecular pathogenesis of bipolar disorder (BPD) is poorly understood. Using human-induced pluripotent stem cells (hiPSCs) to unravel such mechanisms in polygenic diseases is generally challenging. However, hiPSCs from BPD patients responsive to lithium offered unique opportunities to discern lithium's target and hence gain molecular insight into BPD. By profiling the proteomics of BDP-hiPS...

Long inverted repeats (LIRs) have been shown to induce genomic deletions in yeast. In this study, LIRs were investigated within ±10 kb spanning each breakpoint from 109 human gross deletions, using Inverted Repeat Finder (IRF) software. LIR number was significantly higher at the breakpoint regions, than in control segments (P < 0.001). In addition, it was found that strong correlation between 5...

We positionally match a sample of infrared-selected young stellar objects, identified by combining the Spitzer Galactic Legacy Infrared Mid-Plane Survey Extraordinaire, Wide-field Infrared Survey Explorer and Herschel Space Observatory Herschel infrared Galactic Plane Survey, to the dense clumps identified in the millimetre continuum by the Bolocam Galactic Plane Survey in two Galactic lines of...

Restoration and maintenance of intravascular volume is crucial in acute pancreatitis to prevent hypotension and ensure normal organ perfusion. This study evaluated the hemodynamic and metabolic effects of adequate versus inadequate fluid replacement on the pancreas in a canine model of acute experimental pancreatitis. Bile-trypsin pancreatitis (BTP) was induced in 14 conditioned mongrel dogs. L...

The initial results of a millimeter (CO) survey of infrared-excess, optically-selected quasars from the Palomar-Green (PG) Bright Quasar Survey (BQS) with redshifts in the range 0.04 < z < 0.17 are presented. These observations represent the first step towards establishing with a complete sample whether or not quasi-stellar objects (QSOs) reside in molecular gas-rich galaxies, as well as toward...

AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons are specifically located in the subgranular layer (SGL) of dentate gyrus and may be relevant for hippocampal neurogenesis. The focus of this work is aimed to determine local ...

The cellular localization of the nerve growth factor-like immunoreactivity (NGF-LIR) has been studied in the intact adult rat brain at the level of the hippocampus and the septum. Immunolabelling for NGF combined with counterstaining with cresyl violet and double immunostaining technique, which allowed simultaneous localization of NGF-LIR and that of astroglial marker -GFAP, were used. The data...

This paper considers the problem of simple linear regression with intervalcensored data. That is, n pairs of intervals are observed instead of the n pairs of precise values for the two variables (dependent and independent). Each of these intervals is closed but possibly unbounded, and contains the corresponding (unobserved) value of the dependent or independent variable. The goal of the regress...