hepatitis b infection is the main cause of liver related mortality in many countries including iran. liver transplantation in cirrhosis due to hbv infection before 1990 was an absolute contraindication. recurrent infection was a significant event in post liver transplant setting and resulted in increased risk of graft failure and death except successful transplanted individuals. advances in ant...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

background: the radioprotective effect of grewia asiatica fruit (gae) which contains anthocyanin type cyanidin 3- glucoside, vitamin c, a, minerals, carotenes and dietary fibers etc was studied. materials and methods: for study swiss albino mice were divided into five groups-1. control (vehicle treated) 2. gae treated (700 mg / kg. b.wt / day for fifteen days), 3. irradiated (5 gy), 4. gae + ir...

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...

results roc-derived spo2 threshold of ≤ 94% can predict hypoxemia (pao2 < 60 mmhg) with a sensitivity of 100% and a specificity of 95%. furthermore, there are associations between the roc-derived spo2 threshold of ≤ 97% and detection of hypoxemia (pao2 < 70 mmhg) with a sensitivity of 100% and a specificity of 46%. the accuracy of pulse oximetry was not affected by the severity of liver disease...

conclusions it seems that surrogate liver function tests and adipocytokine levels were correlated with the histologic findings of the liver. objectives the aim of the study was to evaluate the correlation between serum adipocytokines and the histologic findings of the liver in patients with non-alcoholic fatty liver disease (nafld). patients and methods this case-control study was performed on ...

the percentage of fat in liver wet and dry matter, liver moist and dry matter and their relationship were investigated based on species, sex and age of 384 slaughtered animals including 114 cows, 100 buffaloes, 147 sheep and 23 goats from 2008 to 2010 in urmia, iran. mean percentage of fat in liver wet and dry matter, and liver dry matter in cows were 3.6%, 1.1%, 29.7%, buffaloes were 5.3%, 1.5...

Introduction Valproic acid (VPA, Valproate) is an eight-branch fatty acid and varies from other antiepileptic drugs. VPA use might lead to mild to severe hepatotoxicity. The aim of this study was to investigate valproic acid impact on liver transaminases at the beginning of VPA treatment and after three and six months of it. Materials and Methods This study was designed as a cross sectional pro...

conclusions hepatocyte isolation can be performed as the main and initial step for cell transplantation from unused/rejected liver. it is the first experience in iran. results highly quality hepatocytes with high viability and low contamination were isolated. the mean viability was 71.8% ± 21.7. in the first 4 cases microbial contamination by staphylococci, diphtheroid and klebsiella was detect...