background: recent studies demonstrated that resveratrol has many therapeutic effects on liver disorders. resveratrol significantly increased survival after liver transplantation, decreased fat deposition, necrosis, and apoptosis which induced by ischemia in wistar rats. it provided liver protection against chemical, cholestatic, and alcohol injury. resveratrol can improve glucose metabolism an...

conclusions nx-dcp correlated positively with fibrosis stage and could discriminate well between hcv-related patients with or without significant fibrosis. moreover, nx-dcp had a similar predictive ability to the abovementioned models, and thereby could be a new noninvasive prediction tool for fibrosis. results increase in serum nx-dcp was significantly related to increase in fibrosis stage (p ...

conclusions hepatoprotective agents combined with antiviral drugs can significantly improve liver function and liver fibrosis parameters in patients with hepatitis b. results a total of 22 randomized controlled trials encompassing 1,714 cases were considered in the meta-analysis. the obtained results indicated that the combination of antiviral drug and hepatoprotective agent was better than ant...

Objective: Liver fibrosis is the primary sign of chronic liver injury induced by various causes. Thymoquinone (TQ) is the major ingredient of Nigella sativa with several beneficial effects on the body. In the present study, we aimed to investigate the effect of TQ on liver fibrosis in a lipopolysaccharide (LPS)-induced inflammation in male rats. Materials and methods: Fifty male Wistar rats wer...

results in a group of adult patients with chb, anxa2 values were far higher than those of the control group (p = 0.001). when we assessed anxa2 levels based on fibrosis stages, serum anxa2 levels of patients with early stage fibrosis (stages 1 - 3) were significantly higher than those of patients with advanced stage fibrosis (stages 4 - 5; p = 0.001). patients and methods this study included 17...

liver fibrosis is a potentially reversible response to hepatic insults, triggered by different chronic diseases most importantly viral hepatitis, alcoholic, and non-alcoholic fatty liver disease. in the course of the chronic liver disease, hepatic fibrogenesis may develop, which is attributed to various types of cells, molecules, and pathways. activated hepatic stellate cell (hsc), the primary ...

background: in patients with hepatitis b and c, environmental factors such as smoking and alcohol can cause liver fibrosis progression. but opium effects on liver fibrosis progression are not clear. this study was designed to assess the relationship of opium user and liver fibrosis progression. methods: in this case-control study, sixty patients in hepatitis b group and sixty patients in hepati...

Introduction: The liver fibrosis is caused by extracellular accumulation of cluster, glycos amino glycans and proteoglycans, which this extracellular accumulation may limit the penetration and molecular movement of water in the tissue, so the Diffusion weighted imaging(DWI) technique is due to the sensitivity to the movement and release of water molecules Can show this restrict...

conclusions according to the results obtained in our study, advanced age, higher bmi, ast, alt, and hbv-dna levels, and low albumin and platelet levels are correlated with advanced fibrosis in patients with chb. objectives this study evaluated the correlation between hepatic fibrosis and routine laboratory values in patients with chronic hepatitis b. patients and methods the files of 456 patien...