Uncoupling of oxidative phosphorylation (OXPHOS) in brown adipose tissue can be used by hibernating animals to produce heat at the expense of their fat mass. In a recent work, Dr Shulman et al. generated a liver-targeted derivative of the prototypical OXPHOS uncoupler 2,4-dinitrophenol that alleviated steatosis, hypertriglyceridemia and insulin resistance in several models of nonalcoholic fatty...

this study is an attempt at a colonial and postcolonial reading of joseph conrad’s lord jim. it is specifically focused on the narrative strategies used in the novel. in other words, it investigates the connection between the narrative strategy and a possible tone of imperialism in conrad’s novel. for the introduction, a brief review of conrad’s manner of writing and his peculiar ambiguity is p...

squalid houses commanding even the most distant view of the proceedings were full of boys and girls anxious to catch a glimpse of the Prince. His Royal Highness, who passed to the platform amid terrific cheering, was accompanied by various officials of Guy's, and took his seat between Lord Goschen, the Treasurer of the Hospital, and Mr. Herbert Waring, Vice-Chancellor of the University of Londo...

1. “LAUDATO SI’, mi’ Signore” – “Praise be to you, my Lord”. In the words of this beautiful canticle, Saint Francis of Assisi reminds us that our common home is like a sister with whom we share our life and a beautiful mother who opens her arms to embrace us. “Praise be to you, my Lord, through our Sister, Mother Earth, who sustains and governs us, and who produces various fruit with coloured f...

OBJECTIVES To examine the reliability and validity of the Clock Drawing Test when used as a cognitive screening instrument for mild to moderate dementia, and to compare different scoring mechanisms. DESIGN Retrospective analysis of clock drawing performance using three published scoring methods (Shulman, Sunderland and Wolf-Klein). SETTING Hospital-based memory disorders clinic. PARTICIPA...

A meeting in support of the British Empire Leprosy Relief Association was held on January 31, at the Mansion House, the Lord Mayor presiding. The Association is appealing for ?250,000 to extend the cure for leprosy which is believed to have been found, and also to continue research work. The speakers were Lord Chelmsford, Chairman of the Association, the Duke of Devonshire, Sir Humphrey Rollest...

The Moran collection, which has been catalogued over the last two years, has presented the archivist with a number of interesting problems, besides those normally associated with a collection of personal papers. The extensive collection' had been used by Professor Lovell for his biography of Lord Moran while it was still at the family homes and it was following an approach by the archivist of t...