Linear programs (LPs) can be solved by polynomially many moves along the circuit direction improving objective most, so-called deepest-descent steps (dd-steps). Computing these is NP-hard (De Loera et al. (2019)), a consequence of hardness deciding existence an optimal circuit-neighbor (OCNP) on LPs with non-unique optima. We prove OCNP easy under promise unique optima, but already O(n1??)-appr...

background: to assess the efficacy of luteal phase support (lps) with vaginal progesterone (p) on pregnancy rates of the stimulated intrauterine insemination (iui) cycles in couples with unexplained infertility (uei). materials and methods: this was a single-center, prospective, randomized, blinded control trial undertaken at a tertiary care university fertility center between october 2007 and ...

Introduction: Gap junctions are intercellular membrane channels that provide direct cytoplasmic continuity between adjacent cells. This communication can be affected by changes in expression of gap junctional subunits called Connexins (Cx). Changes in the expression and function of connexins are associated with number of brain neurodegenerative diseases. Neuroinflammation is a hallmark of vario...

The Last Planner System (LPS) is a production planning and control system that utilizes the lean construction philosophy to improve workflow reliability. Although there are several metrics developed measure performance of LPS, current fail genuinely reflect actual LPS. literature review shows no evidence existing researches provide holistic approach Consequently, this research aims propose new ...

Osteonecrosis (ON) is characterized through the impairment of osseous blood flow that leads to the collapse of femur head. Corticoid-induced ON in rats and lipopolysaccharide (LPS)-induced in rabbits are useful models to assess the efficacy of potential treatments on this disease. D-003 inhibits the mevalonate pathway, lipid peroxidation and prevents osteoporosis in rats through increasing the ...

Abstract The objective was to evaluate the influence of dams grazing endophyte-infected tall, toxic, fescue (E+) during gestation on innate immune response male offspring an endotoxin challenge. Crossbred pregnant multiparous cows (n = 36) bred Red Angus sires were housed in replicated E+ or novel endophyte-infected, non-toxic, (NE+) pastures before breeding and through length gestation. After ...

Abstract Because the macrophage responses to lipopolysaccharide (LPS) might determine direction of clinical manifestations sepsis (severe infection), impacts enhancer zeste homologue 2 (Ezh2; a histone lysine methyltransferase epigenetic regulation) were explored. The transcriptomic analysis on LPS-activated wild-type macrophages demonstrated an alteration several enzymes. Although Ezh2 silenci...