background : the data related to patients often have very useful information that can help us to resolve a lot of problems and difficulties in different areas. this study was performed to present a model-based data mining to predict lung cancer in 2014. methods : in this exploratory and modeling study, information was collected by two methods: library and field methods. all gathered variables w...

this case series reports 100 patients with lung cancer and their presenting neurologic symptoms and sings. 78% of patients were maleand 22% were female. mean age was 62±1.04 years with a peak age between 65 and 75 years. most patients presented with pulmonary problems (58%) and neurologic deficits as the presenting manifestations were found to be 30% along with pulmonary symptoms and 12% laking...

Background: The dosimetric parameters required in lung cancer radiation therapy are taken from a homogeneous water phantom; however, during treatment, the expected results are being affected because of its inhomogeneity. Therefore, it becomes necessary to quantify these deviations.Objective: The present study has been undertaken to find out inter- and intra- lung density variations and its dosi...

Introduction: Despite improvements in the diagnosis and treatment of lung cancer in the past two decades, it has remained the most common cause of death from cancer worldwide. Among all genes that are mutated in lung cancer, TP53 located on chromosome 17P13/1 has a significant diagnostic and prognostic value. TP53 mutations have been extensively studied in lung cancer and TP53 mutational spectr...

Background: An association between lung cancer and chemokines has been advocated in the recent years. This study aims at investigating the association between lung cancer and 16C/A single nucleotide polymorphism (SNP) (rs. 4359426) in C-C motif chemokine 22 (CCL22) as well as C1014T SNP (rs. 2228428) in C-C chemokine receptor type 4 (CCR4), which serves as the receptor for CCL22.Methods: Genoty...

Herein, we reported on a case of solid type of pulmonary actinomycosis in a 10-year-old boy. He had productive cough for 40 days. Bronchoscopy was normal. Cmputed tomography revealed a solid large mass in the upper lobe of his left lung with mimicking malignant leisions. He was referred for surgery and underwent left upper lobectomy. Macroscopically, the specimen measured 13×9×5 cm and was crea...

lung cancer is still diagnosed in advanced stage and most patients do not have the opportunity for surgical treatment. although in the recent years new diagnostic equipment is available such as the radial and linear endobronchial ultrasound (ebus) and electromagnetic fiberoptic bronchoscopy. however; novel targeted therapies with tyrosine kinase inhibitors of second generation and immunotherapy...

it has been observed that lung cancer either non-small cell or small cell is responsible for eye metastases. this form of metastases in several cases was the first manifestation of the disease and further investigation led to the diagnosis of the underlying malignancy. both types of lung cancer are equally responsible for this demonstration. furthermore; both chemotherapy and tyrosine kinase in...

Lung cancer is among the most common cause of cancer death in the world. Since the disease is diagnosed in the middle or late stages of the cancer development a more efficient method for an early diagnosis of the disease is required. The main goal of this study was to investigate the correlation between aberrant promoter methylation of the two genes: SHOX2(Short stature homeobox 2) and WT1(Wilm...