Background: The first recognition of a cluster COVID-19 patients in China late 2019, has become major concern due to its greater transmissibility and vulnerability the patient turn fever, cough, breathlessness, pneumonia then eventually severe acute respiratory distress syndrome requiring intensive care unit (ICU) support. But most affected get cured following mild symptoms very only few them h...

Purpose: The aim of our study is to investigate the prognostic value Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte (MLR), and platelet-to-lymphocyte (PLR) in determining mortality patients hospitalized for intensive care unit (ICU) sepsis. Materials Methods: This retrospectively evaluates all with sepsis ICU between February 2017 April 2018. In addition demographic clinical chara...

Neutrophil-to-Lymphocyte ratio (NLR) is a simple parameter used for easy assessment of the inflammatory status subject. NLR calculated by dividing absolute neutrophil count definite lymphocyte count. reflects balance between innate and adaptive immune systems. Recently, has been as an essential biomarker inflammation, infections, postoperative complications displayed correlation with circulatin...

OBJECTIVES Limited information is available concerning the post-treatment neutrophil-lymphocyte ratio in critical limb ischemia patients who receive conservative therapy. Accordingly, this study was designed to evaluate the predictive value of the post-treatment neutrophil-lymphocyte ratio in critical limb ischemia patients without surgery. METHOD From January 2009 to January 2011, critical l...

NISHIHIRA, T. and FUJII, G. Mixed Lymphocyte-Platelet Lymphocyte-Kidney Cell and Lymphocyte-Liver Cell Reactions in Rats. Tohoku J. exp. Med., 1972, 108 (1), 1-7 The lymphocyte-platelet reaction (MLPR) in various donor recipient combinations in rats showed a nearly coincident relationship with the mixed lymphocyte culture reaction (MLC). The kidney cells had not enough stimulating effect agains...

An impairment in lymphocyte response to mitogen stimulation, a correlate of cell-mediated immunity, has been reported in patients with depressive illness. To investigate whether such impairment in lymphocyte function is related to excessive secretion of cortisol, an immunosuppressive hormone, we compared mitogen-induced lymphocyte proliferation in three groups of subjects: depressed patients wi...

Background: Toxoplasma gondii is an obligate intracellular parasite that infects all mammalian cells. Several antigens such as excreted/secreted antigens have been identified as a potential vaccine candidate. Objective: To determine how excreted/secreted antigens from peritoneal exudates of infected mice (mESA) stimulate cell-mediated immune responses and induce protective immunity against toxo...

FTY720 (2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) is an orally available immunomodulatory agent that induces severe peripheral blood lymphopenia. Most studies of these lymphopenic effects have been limited to short-term exposure to FTY720. FTY720 alters the ability of lymphocytes to respond to sphingosine-1-phosphate (S1P) through S1P receptors, particularly S1P1. FTY720...

Lymphocytes bound at endothelial cell junctions extravasate within minutes. Lymphocyte-endothelial cell binding is mediated by receptors such as vascular cell adhesion molecule 1 (VCAM-1). VCAM-1 activates endothelial cell nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in minutes, and this activity is required for VCAM-1-dependent lymphocyte migration. In this report, we examined m...

PURPOSE Immune responses following stereotactic body radiotherapy (SBRT) for stage I non-small cell lung cancer (NSCLC) were examined from the point of view of lymphocyte subset counts and natural killer cell activity (NKA). PATIENTS AND METHODS Peripheral blood samples were collected from 62 patients at 4 time points between pretreatment and 4 weeks post-treatment for analysis of the change ...