Human T and B lymphocytes differ morphologically and immunologically although little is known concerning their physiological parameters and biochemical constituents. In this study, microviscosity and lipid composition in normal human B and T lymphocytes were investigated. Microviscosity was examined using 1,6-diphenyl-1,3,5-hexatriene as a probe and lipid composition was analyzed by thin-layer ...

Introduction: Non-Hodgkin’s lymphoma (NHL) consists of several hematologic malignancies arising from B, T lymphocytes or natural killer lymphocytes, and nearly 85–90% originates B lymphocytes. This current study illustrates frequency diagnosed NHL cases, age-standardized incidence rate (ASIR) crude (CIR) by age group, year diagnosis administrative regions for identifying the distribution, patte...

Introduction: Moringa oleifera, a member of the family Moringaceae, is small-medium sized tree, widely cultivated in Southeast Asia, Polynesia, and West Indies, where leaves, fruits flowers form part their routine diet. The plant has been reported to possess numerous pharmacological properties; however, its immunomodulatory potentials were least explored, especially on lymphocytes. Therefore, t...

Increased levels of acute-phase reactants and lymphopenia are predictors disease severity in coronavirus 2019 (COVID-19). This study aimed to investigate the role apoptosis etiology patients with COVID-19. multicentered, prospective, case-control was conducted polymerase chain reaction (+) severe acute respiratory syndrome 2 (SARS-CoV-2) patients, an age–gender-matched control group. Samples we...

An autologous mixed lymphocyte reaction was demonstrated between T and non-T lymphocytes. Sheep erythrocyte rosetting was used to separate human lymphocytes into T and non-T lymphoid preparations. Non-T lymphocytes stimulated the proliferation of autologous T lymphocytes. The cell in this preparation that was most stimulatory had the characteristics of a K lymphocyte. The allogeneic mixed lymph...

Six patients with hairy cell leukemia (HCL) were studied for surface immunoglobulin ( sIg ). In all five sIg -positive cases, the heavy chain isotype was IgG. We performed cytologic and cytochemical studies of sIgG + lymphocytes in normal peripheral blood and compared them with hairy cells. Normal sIgM + lymphocytes were also examined. sIgG + and sIgM + lymphocytes made up 0.9% and 6.1% of norm...

Neuraminidase treated T-lymphocytes from normals and CLL gave an enhanced response to PWM when compared to untreated T-lymphocytes. However the overall response of CLL T-lymphocytes was much lower as compared to normals. CLL T-lymphocytes showed an imbalance of T-subsets, where the Tu (Helper) were not only reduced 20.4± 2.96 but also diluted by increased ‘fy (Suppressor) 45 2+5 . 35, when comp...

These experiments describe the preparation of pure marrow-derived lymphocyte suspensions from the thoracic duct of thymectomized, irradiated rats reconstituted with bone marrow cells. The majority of marrow-derived cells were small lymphocytes morphologically indistinguishable from small lymphocytes in thoracic duct lymph of normal donors. Marrow-derived small lymphocytes (B lymphocytes) were a...