This paper describes an experimental prototype of a code generation tool for embedded special-purpose processors. The tool is a retargetable assembly-code-level macro expander capable of program ow analysis. The main advantage of the tool is its strong support for macro hierarchy: hierarchical macro libraries make the code (produced either by the compiler writer or by the assembly language prog...

OBJECTIVES To determine the correlation between various vancomycin MIC testing methodologies and explore the phenomenon of MIC creep. METHODS A total of 417 consecutive non-duplicate methicillin-resistant Staphylococcus aureus (MRSA) bloodstream isolates from Liverpool Hospital between 1997 and 2008 were retrieved. All isolates were classified using PFGE and underwent susceptibility testing f...

MacroH2A is a histone H2A variant that is typically found in heterochromatic regions of the genome. A positively charged linker that connects the histone-fold with the macro-domain was suggested to have DNA-binding properties, and has been shown to promote oligomerization of chromatin fibers. Here we examine the influence of this basic linker on DNA of mononucleosomes. We find that the macro-li...

Histone macroH2A is an unusual core histone that contains a large non-histone region, and a region that resembles a full length H2A. We examined theconservation of this novel structural arrangement by cloning chicken macroH2A cDNAs and comparing them to their rat counterparts. The amino acid sequences of the two known macroH2A subtypes are >95% identical between these species despite evolutiona...

Honu is a new language that contains a system for extending its syntax with an interface built on concrete syntax. Honu combines an existing hygienic macro system with a novel use of a precedence parser to achieve a syntax that is algol-like while maintaining the power of s-expression based macros. We demonstrate how to build the parser and connect it to the underlying macro system.

to test whether they would remove experimentally infested pupae following methods of Boecking and Drescher (1992). In 1994, the hygienic colonies removed significantly more pupae infested with one mite per cell than the non-hygienic colonies. In 1995, there was no significant difference between the hygienic and non-hygienic colonies when one or two mites were introduced per pupa due to variatio...

Der Aufruf zur Mitarbeit in obigem Arbeitskreis, der in den SW-Technik-Trends Heft 4 vom November 2002 veröffentlicht wurde, war ein voller Erfolg. Daraufhin und anschließend an die kurze Präsentation des Verfassers anlässlich der Tagung „Management und Controlling von ITProjekten“ in Glashütten vom 28.-29.03.2003 meldeten sich bisher 17 Mitglieder. Einige davon trafen sich auch schon in Dortmu...

Histones are a major component of chromatin, the nucleoprotein complex fundamental to regulating transcription, facilitating cell division, and maintaining genome integrity in almost all eukaryotes. In addition to canonical, replication-dependent histones, replication-independent histone variants exist in most eukaryotes. In recent years, steady progress has been made in understanding how histo...

For thirty years, from the early 1840s, Charles Darwin documented the disappearance of flints in the grounds of Down House in Kent, at a location originally known as the “Stony Field”. This site (Great Pucklands Meadow – GPM) was visited in 2007 and an experiment set up in this ungrazed grassland. Locally-sourced flints (either large – 12 cm, or small – 5 cm dia.) were deposited at two densitie...

A language FOBS-X (Extensible FOBS) is described. This language is an interpreted language, intended as a universal scripting language. An interesting feature of the language is its ability to be extended, allowing it to be adapted to new scripting environments. The interpretation process is structured as a core-language parser back-end, and a macro processor frontend. The macro processor allow...