The translocation of large macromolecules through the nuclear pore complex (NPC) of eukaryotic cells is hindered by the phenylalanine-glycine (FG) nucleoporin (Nup) barrier unless molecules are chaperoned by transport receptors. The precise mechanism of facilitated translocation remains unclear due to the challenges of measuring the series of transient interactions between a transport receptor ...

   Graphene oxide nanosheet (GONS) can be a suitable membrane for gas separation with high permeability and selectivity. Separation of N2/CO2 using functionalized GONS was investigated by molecular dynamics simulations. The simulated systems were comprised of two types of GONS with a pore in their center, N2 and CO2 molecules. The selectivity and ...

pore pressure is an important parameter, in exploration and production of hydrocarbon resources. lack of accurate knowledge about pore pressure, before drilling phase, leads to serious dangers in drilling process. accurate knowledge about distribution of pore pressure in a field, leads to reduce risks in drilling, improve well planning and mud weight calculations. during burial, normally pressu...

The nuclear pore complex (NPC) arose in evolution as the cell's largest and most versatile transport channel. Current models for selective transport mediated by NPCs are focused on properties of intrinsically disordered regions of nucleoporins that bind transport factors. In contrast, structured regions are considered to provide static anchoring sites for the disordered regions without affectin...

The three-dimensional structure of the nuclear pore complex has been determined to a resolution of approximately 90 A by electron microscopy using nuclear envelopes from Xenopus oocytes. It is shown to be an assembly of several discrete constituents arranged with octagonal symmetry about a central axis. There are apparent twofold axes perpendicular to the octad axis which suggest that the frame...

The symmetric core of the nuclear pore complex can be considered schematically as a series of concentric cylinders. A peripheral cylinder coating the pore membrane contains the previously characterized, elongated heptamer that harbors Sec13-Nup145C in its middle section. Strikingly, Sec13-Nup145C crystallizes as a hetero-octamer in two space groups. Oligomerization of Sec13-Nup145C was confirme...

An understanding of how the nuclear pore complex (NPC) mediates nucleocytoplasmic exchange requires a comprehensive inventory of the molecular components of the NPC and a knowledge of how each component contributes to the overall structure of this large molecular translocation machine. Therefore, we have taken a comprehensive approach to classify all components of the yeast NPC (nucleoporins). ...

Abstract In this work, the compressive properties of sintered nano-silver applied to third generation semiconductor at room temperature are tested a loading rate 10 -2 s -1 . The stress-strain curve shows obvious elastic and plastic stage, with failure pore wall sintering neck, damage accumulates gradually until failure. microstructure is analyzed statistically by scanning electron microscope. ...

The processes of shale gas transport and enrichment are closely related to the micro-fractures structure. Here, porosity, permeability test, adsorption, scanning electron microscopy (SEM), fluid spontaneous imbibition, Nano-CT, Micro-CT, core observations were used determine types characteristics in Longmaxi shales, Jiaoshiba area. effects on reservoir properties accumulation also analyzed. Div...