نتایج جستجو برای: macrophage

تعداد نتایج: 53700  

Journal: :iranian biomedical journal 0
مهریار حبیبی رودکنار mehryar habibi roudkenar سعید بوذری saeid bouzari yoshikazu kuwahara آمنه محمدی روشنده amaneh mohammadi taisuke baba مانا علومی mana oloomi

background: immunotoxins are comprised of both the cell targeting and the cell killing moieties. we previously established a new immunotoxin, i.e. shiga toxin granulocyte macrophage-colony stimulating factor (stxa1-gm-csf), comprises of catalytic domain of stx, as a killing moiety and gm-csf, as a cell targeting moiety. in this study, the ability of the immunotoxin to induce apoptosis and doubl...

Journal: :International Journal of Molecular Sciences 2023

Macrophage polarization is influenced by lipids, which also exert significant control over macrophage functions. Lipids and their metabolites are players in intricate signaling pathways that modulate macrophages’ responses to pathogens, phagocytosis, ferroptosis, inflammation. This review focuses on lipid metabolism functions addresses potential molecular targets for the treatment of macrophage...

Journal: :Theranostics 2021

Macrophages are specialized cells that control tissue homeostasis. They include non-resident and tissue-resident macrophage populations which characterized by the expression of particular cell surface markers secretion molecules with a wide range biological functions. The differentiation polarization macrophages relies on specific growth factors their receptors. Macrophage-colony stimulating fa...

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

Journal: :international journal of bio-inorganic hybrid nanomaterials 0

magnetic nanoparticles are the good choice for using in mri as the contrast agent. iron oxide particles such as magnetite (fe3o4) or its oxidized form maghemite (γ-fe2o3) are the most commonly employed in biomedical applications. in this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (cmn-fe nps) and evaluated its ability for the mice macrophage ...

Journal: :iranian journal of allergy, asthma and immunology 0
farzaneh rezazadeh marznaki institute of biochemistry and biophysics, department of biochemistry, university of tehran, tehran, iran raheleh shakeri institute of biochemistry and biophysics, department of biochemistry, university of tehran, tehran, iran sussan kaboudanian ardestani institute of biochemistry and biophysics, department of biochemistry, university of tehran, tehran, iran azar tahghighi department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran alireza foroumadi department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran

it   was   recently   demonstrated   that   5-(5-nitrofuran-2-yl)-1,   3,   4-thiadiazoles   with piperazinyl-linked benzamidine substituents are effective in vitro against leishmania major. following on this evidence, we used colorimetric assay of acid phosphatase activity in the promastigotes  as  an  indicator  for  cell  viability.  also  we  studied  the  effect  of  these compounds on ind...

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

Journal: :International Journal of Experimental Pathology 2004

Journal: :Translational Oncology 2021

Human stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. The role of STC1 in the pro- anti-inflammatory functions differentiating macrophage, however, not clear. In this study, our data showed that phorbol 12-myristate 13-acetate (PMA) treatment induced human leukemia monocytic cells (ThP-1) differentiation to M0 macrophages. was accompanied by signifi...

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