Macrophages are immune cells that play critical roles in both inflammation and tissue homeostasis. Classically activated (M1) macrophages promote antimicrobial tumoricidal activity, while alternatively (M2) phagocytosis The facilitative GLUT1 GLUT3 hexose transporters expressed abundantly different hematopoietic lineages, but their specific macrophages, leukocytes general is poorly understood. ...

neuropeptides, possessing specific and functional receptors on various cells of the immune system, have the potential to regulate immune responses; and the macrophages as important components of defense against various agents, are at their influence. in this study the effect of neuropeptides substance p (sp) and calcitonin gene-related peptide (cgrp) on il-1 beta production by herpes sim¬plex t...

one of the mechanisms involved in the regulation of the immune system by steroid hormones could be the monocytic-macrophage system. in this study the effect of the male hormone 5a-dht on cytokine release by peritoneal macrophages (mφ) of male and female nzb/balbc mice was investigated. macrophages from male mice activated with lps produced a greater amount of il-1β (21.8%) (p<0.05) and il-6 (19...

background: the leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. methods: essential oils were obtained by the steam distillation of plant leaves without any prior processing. cytotoxicity was tested on j774 macrophages and leishmanicidal activity was assessed against four species of leishmania associated with cutaneous leishmaniasis ....

Macrophages are key components of the innate immune system. The variability macrophage’s participation in tumor progression, determined by their functional polarization, opens up a wide prospect for modulating profile, primarily direction increasing antitumor activity. purpose study was to provide up-to-date data on process macrophage mechanisms its regulation, polarization markers and inductio...

In this paper, we studied a mathematical model of tuberculosis with vaccination for the treatment tuberculosis. We considered an in-host that described interaction between Macrophages and Mycobacterium investigated effect treatments on uninfected macrophages. Optimal control is applied to show optimal effective strategies disease. The formula obtained using Hamiltonian function Pontryagin's max...

Background: The water-soluble extract of Ganoderma lucidum (Reishi) has been used as an immunomodulator to stimulate spleen cells proliferation and cytokine expression. Objective: To investigate the effect of Ganoderma lucidum (G. lucidum) on cytokine production by mice peritoneal macrophages. Methods: Mice peritoneal macrophages were prepared by intra-peritoneal injection of 5 ml cold PBS. Per...

introduction: it has been shown that gama-ifn is one of the major cytokines involved in lung fibrosis. it has also been demonstrated that nitric oxide (no) may exert vasodilation, edema and cytotoxicity, and it may stimulate cytokinedependent processes in the lungs. in this study, the effect of 17-beta estradiol (17-betae2) and five alpha dihydrotestosterone (5alfa-dht) on no release by tgf bet...

the endotoxin dose response of recruited and activated tissue macrophages isolated from a rat model of liver injury has been measured after 24 hours in in vitro culture, with respect to their production of a lysosomal enzyme, n-acetyl-glucosaminidase (tlag). there were no significant differences in the nag activity in cell lysates or supernatants following a two-hour exposure of the macrophages...