Psychotropic drugs (antidepressants, antimanic drugs, antipsychotics, analgesic opioids, and others) are among the most frequently used medicines. Between these drugs and magnesium there are pharmacokinetic and pharmacodynamic interactions. Erythrocyte magnesium is decreased in patients with severe major depression (MD) vs normal subjects (44 +/- 2.7 mg/L in MD group vs 59.1 +/- 3.2 mg/L in con...

OBJECTIVE To estimate whether magnesium therapy is the optimal management for women with mild preeclampsia. METHODS A decision analytic model was designed for women with mild preeclampsia to estimate whether empiric magnesium therapy or no magnesium therapy is the optimal management strategy. The model considered relevant clinical events: seizure, placental abruption, and magnesium toxicity. ...

Magnesium is an essential ion that has an important role in regulating cell cycles and maintaining genomic stability (1). Administration of supplemental magnesium in animals with experimentally induced colon cancer resulted in fewer colon tumors and smaller cryptal cells of the colon (2), suggesting an inhibitory role of magnesium in colon cancer cell proliferation. The mechanism by which magne...

migraine is one of the common varieties of headache. it involves 4 to 6 percent of men and 13 to 16 percent of women under 30 years in more than 80% of cases. some studies have shown that in 50% of patients serum magnesium level decreases during attacks of headache and using magnesium tablets and intravenous magnesium sulfate is more effective for treatment of migraine attack, than placebo. thi...

conclusions magnesium at low dose decreases sore throat and pain severity more effectively compared to ketamine gargle. results there were no significant differences between age, sex, and body mass index (bmi) between two groups of patients. hemodynamics of patients, including blood pressure, respiratory rate, oxygen saturation %, and conscious state were not significantly different (p > 0.05)....

Hypomagnesemic tetany of ruminants is a nonHistory and observation infectious metabolic disorder that occurs in a wide The five young calves with a history of staggering range of nutritional and managemental conditions gait and an inability to stand up were presented to the (Smith and Edward, 1988). This condition occurred due peripheral veterinary hospital, shimoga. The calves to magnesium def...

magnesium is an essential metal that has important roles in physiological function of the body organs. ethambutol is an oral antitubercular agent with chelating effects owing to its chemical structure. the aim of present study is to determine whether ethambutol usage can alter serum magnesium concentration in patients with pulmonary tuberculosis. sixty patients with diagnosis of pulmonary tuber...

We investigated the role of extracellular magnesium on capillary endothelial cell migration and proliferation, components of endothelial cell function that play an important role in angiogenesis and wound healing. Cell migration and proliferation were tested in six different MgSO4 concentrations and in various culture conditions. The Boyden chamber procedure was used to evaluate migration of bo...

To examine whether or not magnesium suppresses coronary spasm, the effect of magnesium infusion on anginal attacks induced by hyperventilation was studied in 20 patients with variant angina. In all patients, anginal attacks associated with ischemic ST segment changes on the electrocardiogram were repeatedly induced by hyperventilation. The study was performed in the early morning successively f...

OBJECTIVE Magnesium historically has been used for treatment and/or prevention of eclampsia or preterm labor. More recently, antepartum magnesium sulfate has been suggested for prevention of cerebral palsy in preterm infants. Although adverse effects and toxicity of magnesium in pregnant women are well known, the fetal-neonatal effects of magnesium are less clear. The objective of this study wa...