magnesium sulfate is widely used in obstetrics and is drug of choice in two important complications of pregnancy, preeclampsia and preterm labor. the antagonistic effects of magnesium sulfate on calcium ion and on platelet aggregation may lead to changes in bleeding time. this study was conducted to evaluate the effect of magnesium sulfate on bleeding time in women with threatened preterm labor...

based on a number of studies, magnesium sulfate (mgso4) given after a diffuse axonal injury has gained attention as a useful neuroprotective agent .the present study was conducted to examine if magnesium sulfate has a therapeutic efficacy and safety in patients with a severe diffuse axonal injury. adult patients admitted within 1 hour of a closed traumatic brain injury (tbi) with a severe diffu...

introduction: renal colic can be managed by preventing the contraction movements of ureter muscles. by reducing acetylcholine in the nerve terminals, magnesium sulfate could be effective in this regard. the aim of this study is to investigate the effect of magnesium sulfate on acute renal colic pain relief. method: the present study was a double-blind clinical trial in which the patients suffer...

OBJECTIVE To investigate the effects of two tocolytics, nifedipine and magnesium sulfate, on Doppler indices in maternal and fetal vessels. MATERIALS AND METHODS We recruited 100 pregnant women with preterm birth between 24-36 gestational weeks who were admitted to our tertiary center over a two-year period. Patients were allocated to nifedipine (n=49) and magnesium sulfate (n=51) groups and ...

though intravenous (iv) magnesium sulphate (mgs04) has additive effect to beta-2 agonists, its additive benefit in face of combination therapy with beta-2-agonists and ipratropium (standard therapy of severe acute exacerbation of asthma) remains unaddressed. the aim of this investigation was to evaluate the role of iv mgso4 when used as an adjunct to standard therapy of severe exacerbations of ...

conclusions this study showed that the addition of intrathecal magnesium sulfate to bupivacaine is not desirable in patients undergoing cesarean section due to the delay in the onset of sensory blockade and the lack of significant effects of magnesium on post-operative pain. results the onset of sensory blockade was delayed in case group compared with control group, and this was statistically s...

conclusions intravenous magnesium sulfate with dose of 15 mg/kg could not prevent laryngospasm and coughing after removal of the endotracheal tube in patients undergoing adenotonsillectomy; however, it reduced coughing and laryngospasm in the magnesium sulfate group compared with the control group. results laryngospasm was not found in the magnesium sulfate group; however, its incidencewas5.7% ...

background new drugs are increasingly used to induce analgesia during surgeries. this study compared the analgesic effects of paracetamol and magnesium sulfate. methods sixty patients with american society of anesthesiologists (asa) class i or ii patients who were candidates for surgery of the lower limbs were randomly divided into three equal groups who were age and gender matched. group 1 rec...

background there have been many concerns about alteration in hemodynamic parameters within and shortly after endotracheal intubation (eti) in patients scheduled for elective coronary artery bypass grafting (cabg). objectives we compared the attenuation effect of magnesium sulfate and lidocaine on hemodynamic responses after eti, in patients undergoing cabg. patients and methods in this randomiz...

OBJECTIVES To determine the response of nebulized magnesium sulfate on the lung function of acetylcholine-induced asthma children. METHODS Three hundred and thirty children of asthma with positive bronchial provocation test were randomly divided into three groups: magnesium sulfate, albuterol, and a combination of magnesium sulfate and albuterol. Lung function was compared between the three g...