Superoxide dismutase (SOD) is the first line of defense against oxidative damage. Malathion an organophosphate insecticide and can induce production reactive oxygen species (ROS) cause intracellular stress. The present study was undertaken to examine effects malathion on SODs activity their transcriptional levels in Oxya chinensis (Thunberg) (Orthoptera: Acrididae). results showed that total SO...

Developmental neurotoxicity (DNT) refers to the toxic effects induced by various chemicals on brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have significant effects on brains during early childhood. Some toxicants have been confirmed to induce developmental toxic effects on CNS; however, most of agents cannot be identified wi...

Different genetic biomarkers have been used to evaluate the mutagenic effects of pollutants such as agriculture pesticide and also a great variety of chemicals delivered on the environment by human activities. This way, the aim of present study was to evaluate the effect of agriculture pesticide in Channa punctatus through the micronucleus test as cytogenetic parameter and Haematological studie...

BACKGROUND Workers in pesticide manufacturing industries are constantly exposed to pesticides. Genetic biomonitoring provides an early identification of potential cancer and genetic diseases in exposed populations. The objectives of this biomonitoring study were to assess DNA damage through comet assay in blood samples collected from industry workers and compare these results with those of clas...

The pollution of rivers and streams with chemical contaminants has become one of the most critical environmental problems of the century. As a result of the pollutants transport from industrial areas into the environment and their chemical persistence, many freshwater ecosystems are faced with spatially or temporally alarming high levels of xenobiotic chemicals (Brack et al., 2002; Diez et al.,...

Cancer progression has been associated with an increase in genomic instability indicated by inactivation of tumor suppressor genes and activation of oncogenes. Epidemiological and experimental evidence has implicated estrogens in the etiology of breast cancer. To study environmental organophosphorous pesticides is of interest since evidence indicate that pesticides may enhance cell division, in...

Five organophosphates (OPs) (chlorpyrifos, chlorpyrifos methyl, fenthion, malathion, and temephos), 3 pyrethroids (bifenthrin, cypermethrin, and permethrin), and 2 microbial pesticides (Bacillus thuringiensis serovar.israelensis [B.t.i.] and Bacillus sphaericus) were tested as larvicides against a Florida Aedes albopictus population colonized in the laboratory. In addition, 3 insect growth regu...

The present study was conducted to evaluate the effects of an organophosphorous pesticide malathion on histo-architecture of liver and kidney of common carp exposed to two sub-lethal concentrations (1.5 and 3.0 mg/L) for a period of 8 days. The 96 h LC50 value of malathion for common carp was 15.24 mg/L. Several morphological changes were observed in the liver after exposure to the malathion. H...

malathion is one of the most commonly used pesticides in agriculture. this study was aimed to investigate the acute toxicity of malathion as an aquatic pollutant on the behavior and hematological indices in indian carp ( cirrhinus mrigala ). a static experiment was conducted and 1, 24, 48, 72 and 96 hrs lc 50 values of malathion for the test fish were estimated as 14.55 mg/l, 12.48 mg/l, 11.56 ...

objective(s): in this study the effect of crocin, a carotenoid isolated from saffron, on malathion (an organophosphate insecticide) induced depressive- like behavior in subacute exposure was investigated. moreover the molecular mechanism of malathion induced depressive- like behavior and its decreasing effect on the level of brain derived neurotrophic factor (bdnf) in rat hippocampus and cerebr...