Testicular microlithiasis was found in a 30-year-old infertile man. The literature is reviewed and the possible influence of testicular microlithiasis on male infertility is discussed.

INTRODUCTION REPRODUCTIVE PHYSIOLOGY ANTERIOR PITUITARY TESTES FEEDBACK CONTROL OF GONADOTROPINS PROLACTIN AND GONADOTROPINS ANDROGEN PHYSIOLOGY HORMONAL CONTROL OF SPERMATOGENESIS DIAGNOSING ENDOCRINE ABNORMALITIES: CLINICAL FINDINGS SEMEN ANALYSIS BASELINE HORMONE EVALUATION DYNAMIC HORMONAL TESTING CLASSIFICATION OF ENDOCRINE CAUSES OF INFERTILITY PRIMARY HYPOGONADISM SECONDARY HYPOGONADISM ...

PURPOSE To determine the role of glutathione S-transferases (GSTs; GSTM1, GSTT1, and GSTP1) gene polymorphisms in susceptibility to male factor infertility. MATERIALS AND METHODS We report a pooled analysis of 11 studies on the association of GSTM1, GSTT1, and GSTP1 polymorphisms and male factor infertility, including 1323 cases and 1054 controls. RESULTS An overall significant association ...

Several studies showed that the genetic mutations in the folate-related enzyme genes might be associated with male infertility; however, the results were still inconsistent. We performed a meta-analysis with trial sequential analysis to investigate the associations between the MTHFR C677T, MTHFR A1298C, MTR A2756G, MTRR A66G mutations and the MTHFR haplotype with the risk of male infertility. O...

We asked if essentiality for either fertility or viability differentially affects sequence evolution of human testis proteins. Based on murine knockout data, we classified a set of 965 proteins expressed in human seminiferous tubules into three categories: proteins essential for prepubertal survival ("lethality proteins"), associated with male sub- or infertility ("male sub-/infertility protein...

background: to determine any correlation between infertility and semen quality with concentrations of l-carnitine in human seminal plasma. methods: this case-control study performed in fatemieh hospital in hamadan, iran. seminal plasma of 72 infertile men and 80 men with proved fertility as a control group was investigated and l-carnitine level was determined using uv enzymatic test at 340 nm. ...

background: wide range of disorders ranging from genetic disorders to coital difficulties can influence male fertility. in this regard, genetic factors are highlighted as the most frequent, contributed to 10-15%, of male infertility causes. objective: to investigate the influence of genetic abnormalities on semen quality and reproductive hormone levels of infertile men from northeast china. mat...

background: about 15% of couples have infertility problems which 40% of them are related to the male factors. genetic factors are candidate for about 10% of male infertility conditions. among these, azfa, azfb, azfc and azfd regions on the yq are considered most important for spermatogenesis. microdeletions of these regions are thought to be involved in some cases of azoospermic or oligospermic...

background: it is established that sperm dna integrity is essential in fertilization and normal embryo and fetal development. routine semen analysis gives an approximate evaluation of the functional competence of spermatozoa, but does not always reflect the quality of sperm dna. therefore, the evaluation of sperm dna integrity, in addition to routine sperm parameters, could add further informat...

objective: to investigate the association of c631t single nucleotide polymorphisms in spo11 gene with male infertilityfollowed by an in silico approach. spo11 is a gene involved in meiosis and spermatogenesis process, which in humans, this gene is located on chromosome 20 (20q13.2-13.3) with 13 exons. materials and methods: in a case-control study, 200 blood samples were collected from the ivf ...