intraductal papillary mucinous neoplasms (ipmns) are rare pancreatic tumours, accounting for less of 1-2% of all neoplasms of the gland. main characteristics of ipmns are their favourable prognosis as these pre-malignant or frankly malignant lesions are usually slow-growing tumours and radical surgery is frequently possible. according with the localization of the lesions, three different entiti...

Malignant degeneration of neurogenic tumors has been reported to occur in 1-25% of patients with neurofibromatosis-I, and is the leading cause of cancer-related death in these patients. We report a case of multidisciplinary management of a giant malignant endothoracic nerve sheath tumor leading to histologically proven remission.

OBJECTIVE Hyperglycemia has been shown to augment tumor growth in vitro. However, the effects of persistent hyperglycemia on survival, recurrence and malignant degeneration in patients undergoing surgery for low grade gliomas remain unknown. METHODS All patients who underwent a craniotomy for hemispheric low grade glioma (WHO grade II) from 1996 to 2006 at a single institution were retrospect...

OBJECTIVE It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial low-grade gliomas. METHODS We conducted a retrospective cohort study (n = 170) between 1996 and 2007 at a single institution to determine whether increasing extent of surgical resection was associated with improved progression-free survival (PFS) and ov...

BACKGROUND Dermoid cysts are rare well-differentiated benign tumors derived from ectodermal cell origins. Usually caught incidentally, they have the potential for mass effect, malignant degeneration, and rupture. Dermoid cysts can often present a unique surgical challenge. CASE REPORT A 69-year-old male brought to the emergency department after a motor-vehicle accident had a preperitoneal inc...

BACKGROUND Malignant degeneration in any chronic wound is termed a Marjolin's ulcer (MU). The overall metastatic rate of MU is approximately 27.5%. However, the prognosis of MU specific to pressure sores is poor, with a reported metastatic rate of 61%. This is due to insidious, asymptomatic malignant degeneration, a lack of healthcare provider awareness, and, ultimately, delayed management. C...