conclusions the results of this study supported the potential protective effects of zncl2 on rat kidney tissues against cdcl2 toxicity. results in contrast to the animals that received zncl2, cdcl2 induced a dose-dependent elevation in bun, creatinine, and mda in those without zncl2 pretreatment. zinc chloride had significantly decreased all biochemical parameters and protected kidney cells aga...

BACKGROUND This investigation describes the relationship between glutathione peroxidase activities, an antioxidant enzyme, and the oxidative status in diabetic rat blood. METHODS Malondialdehyde level and glutathione peroxidase activity were measured by spectrophotometric techniques. RESULTS AND CONCLUSIONS Malondialdehyde content in the diabetic rats group was increased compared to that in...

The role of free oxygen radicals in experimental acute pancreatitis induced by common bile duct ligation was investigated by measuring malondialdehyde levels in the rat pancreas. Also, the potential role of leucocytes as the source of free oxygen radicals was tested by inducing leukopenia with methotrexate. The malondialdehyde levels in the control, pancreatitis and pancreatitis + methotrexate ...

Oxidative stress has been postulated as a mechanism of organ dysfunction - and thus a potential therapeutic target - in sepsis. Lorente and colleagues report increased serum levels of malondialdehyde, a biomarker of oxidative stress-induced lipid peroxidation, in adults with severe sepsis, particularly in non-survivors. While survivors exhibited a decrease in serum malondialdehyde over time, th...