oxidative stress arises when there is an imbalance between reactive oxygen species (ross) and scavenging capacity of antioxidants, and it can induce and progress many diseases such as breast cancer. the present study was conducted to investigate the status of plasma antioxidative vitamins (e and c) and lipid peroxidation on 50 untreated breast cancer patients and 50 healthy age-matched women. t...

Previous studies support an early role for neurotransmitter signaling before synaptogenesis, but puzzlingly, a neurological phenotype is absent in embryonic mice that lack vesicular release. Demarque et al. (in this issue of Neuron) now report that early release of transmitter is unconventional in not requiring action potentials, Ca(2+) entry, or vesicle fusion, thus potentially reconciling the...